Results 31 to 40 of about 86,700,063 (188)

Paradoxical Pain in Congenital Insensitivity to Pain: A Systematic Review and Implications for Nociception

Systematic review of case reports of patients diagnosed with "Congenital Insensitivity to Pain" that reported experiencing ...
John Quintner, Asaf Weisman, Youssef Masharawi   +2 more
core   +6 more sources

Congenital insensitivity to pain and anhidrosis

Indian Journal of Orthopaedics, 2011
Congenital insensitivity to pain and anhidrosis (CIPA) is a rare reported entity characterised by disturbance in the pain and temperature perception due to involvement of the autonomic and sensory nervous system. It is an autosomal recessive trait with several defects of the gene NTRK1 coding for the neurotrophic tyrosine kinase - a nerve growth factor
Sasnur, Ashok H, Sasnur, Prakash A, Ghaus-ul, Raza Shamikh Muneer   +2 more
openaire   +3 more sources

Prosthetic Rehabilitation of A Child with Transfemoral Amputation Who Had Congenital Insensitivity to Pain with Anhidrosis

, 2011
Congenital insensitivity to pain with anhidrosis is a rare autosomal-recessive disorder characterized by systemic anhidrosis, insensitivity to pain, mental retardation, osteomyelitis, and joint deformities which could result in amputations.
Ulger, Ozlem, Topuz, Semra, Aksoy, Cemalettin   +2 more
core   +2 more sources

Quantitative corneal neural imaging using in vivo confocal microscopy in cases of congenital corneal anesthesia: A prospective analysis and clinical correlation

Indian Journal of Ophthalmology, 2021
Purpose: Congenital corneal anesthesia (CCA) is a rare clinical entity that poses a diagnostic dilemma, particularly in the pediatric age group with very little literature on this.
Madhumita Gopal, Muralidhar Ramappa, Ashik Mohamed, Rohit Dhakal, Sunita Chaurasia   +4 more
doaj   +1 more source

Total hip arthroplasty in a patient with congenital insensitivity to pain: a case report

Journal of Medical Case Reports, 2012
Introduction Congenital insensitivity to pain, a rare neurological entity, is characterized by varying degrees of sensory loss and autonomic dysfunction. Orthopedic manifestations of congenital insensitivity to pain include delayed diagnosis of fractures,
Erdil Mehmet, Bilsel Kerem, Imren Yunus, Ceylan Hasan, Tuncay Ibrahim   +4 more
doaj   +1 more source

Exploring CNS Involvement in Pain Insensitivity in Hereditary Sensory and Autonomic Neuropathy Type 4: Insights from Tc−99m ECD SPECT Imaging

Tomography, 2023
Hereditary sensory and autonomic neuropathy type 4 (HSAN4), also known as congenital insensitivity to pain with anhidrosis (CIPA), is a rare genetic disorder caused by NTRK1 gene mutations, affecting nerve growth factor signaling. This study investigates
Cheng-Chun Chiang, Yu-Che Wu, Chiao-Hsin Lan, Kuan-Chieh Wang, Hsuan-Ching Tang, Shin-Tsu Chang   +5 more
doaj   +1 more source

Homozygosity for a Rare Plec Variant Suggests a Contributory Role in Congenital Insensitivity to Pain. [PDF]

Int J Mol Sci
Congenital insensitivity to pain is a rare human condition in which affected individuals do not experience pain throughout their lives. This study aimed to identify the molecular etiology of congenital insensitivity to pain in two Thai patients. Clinical,
Kantaputra P, Daroontum T, Kitiyamas K, Piyakhunakorn P, Kawasaki K, Sathienkijkanchai A, Wasant P, Vatanavicharn N, Yasanga T, Kaewgahya M, Tongsima S, Cox TC, Arold ST, Ohazama A, Ngamphiw C.   +14 more
europepmc   +2 more sources

Novel Neurotrophic Tyrosine Kinase Receptor Type 1 Gene Mutation Associated with Congenital Insensitivity to Pain with Anhidrosis

, 2011
Congenital insensitivity to pain with anhidrosis (hereditary sensory and autonomic neuropathy type IV) is a rare autosomal recessive disorder caused by a defect in neurotrophic tyrosine kinase receptor and nerve growth factor, as reported in previous ...
林宜霈;蘇怡寧;翁妏謹;李旺祚, LIN, YI-PEI;SU, YI-NING;WENG, WEN-CHIN;LEE, WANG-TSO   +1 more
core   +1 more source

Anesthetic management during adenotonsillectomy for twins with congenital insensitivity to pain with anhidrosis: two case reports

Journal of Medical Case Reports, 2017
Background Congenital insensitivity to pain with anhidrosis is a rare autosomal recessive disorder characterized by hyperpyrexia, anhidrosis, pain insensitivity, self-inflicted injuries, and intellectual disability.
Cong Wang, Xianwei Zhang, Shanna Guo, Jiaoli Sun, Ningbo Li   +4 more
doaj   +1 more source

Congenital insensitivity to pain with anhidrosis

, 1998
PubMedID: 9651783We present a five-year-old girl with congenital insensitivity to pain with anhidrosis. A skeletal radiographic survey revealed several old fractures.
Polat S., Özbarlas S., Onaç E., Herdem M.   +3 more
core   +2 more sources