Results 41 to 50 of about 86,700,063 (188)

Anesthetic management of a patient with congenital insensitivity to pain with anhidrosis by coadministration of remifentanil

JA Clinical Reports, 2018
Background Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disease characterized by unexplained fever, systemic insensitivity to pain, anhidrosis, and mental distress.
Yoko Takeuchi, Yoshihito Fujita, Takeshi Shimomura, Shuji Kurokawa, Hiroki Noguchi, Yoshihiro Fujiwara   +5 more
doaj   +1 more source

Pregnancy in hereditary sensory and autonomic neuropathy type V: A case report and literature review

Taiwanese Journal of Obstetrics & Gynecology, 2022
Objective: Hereditary sensory and autonomic neuropathies (HSANs) are a clinical heterogenous group of inherited neuropathies featuring prominent sensory and autonomic involvement. We report on the management of pregnancy and delivery in a woman with HSAN
Daisuke Higeta, Akihito Morita, Risa Uehara, Maki Inoue, Takashi Kameda, Akira Iwase   +5 more
doaj   +1 more source

Congenital insensitivity to pain: Review with dental implications

Indian Journal of Pain, 2014
Pain causes a reflex withdrawal from any stimuli that can cause actual or potential tissue damage. It is frequently an early symptom of a disease process and is often the impetus for a patient to seek medical treatment.
A Vijay Kumar, H P Jaishankar, Purnachandrarao Naik   +2 more
doaj   +1 more source

A case of congenital insensitivity to pain with anhidrosis [PDF]

Türk Pediatri Arşivi, 2014
To the Editor, Congenital insensitivity to pain with anhidrosis (CIPA) syndrome is a rare autosomal recessive disease which is also known as hereditary sensory and autonomic neuropathy type 4 (1). The prominent characteristics of the disease include fever due to anhidrosis, absence of sense of pain, painless ulcers in the structures inside the mouth
Ahmet Kağan, Özkaya, Ekrem, Güler, Elif, Arık, Ali Rıza, Namlı, Derya, Cevizli, Olcay, Güngör   +5 more
openaire   +2 more sources

Congenital Insensibility to Pain

Medisur, 2023
Congenital insensitivity to pain is a condition that is present at birth, the affected individual is unable to perceive physical pain. The main symptoms include: wounds, bruises, fractures, self-mutilations, which can go unnoticed due to lack of ...
Carlos Gustavo López Barrionuevo, Génesis Camila Romero Paredes, Byron Omar Montero Carpio   +2 more
doaj  

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Looking for trouble: A common threat‐detection mechanism underlying pain, fear, and anxiety

Mind &Language, EarlyView.
I put forward a novel cognitive architecture for pain, fear, and anxiety, according to which these three capacities are underpinned by a common threat‐detection mechanism. This mechanism takes information about potential threats as input, assesses whether the threat is actual and, if it deems it is, outputs a threat representation.
Luca Barlassina
wiley   +1 more source

Nerve growth factor, pain, itch and inflammation: lessons from congenital insensitivity to pain with anhidrosis [PDF]

, 2010
NGF is a well-known neurotrophic factor essential for the survival and maintenance of primary afferent neurons and sympathetic neurons. NGF is also an inflammatory mediator associated with pain and itch.
インドウ, ヤスヒロ, Indo, Yasuhiro, 犬童, 康弘, 93163, 118261   +4 more
core   +2 more sources

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source