Results 11 to 20 of about 4,501 (218)

Maternal serum Lamin A is a potential biomarker that can predict adverse pregnancy outcomes

EBioMedicine, 2022
Summary: Background: Maternal serum Lamin A (LMNA) was reported to have potential diagnostic value in the prenatal diagnosis of congenital heart disease (CHD).
Lizhu Chen, Yun Xiu, Qijun Wu, Yu Wang, Yixin Zhang, Jia Xue, Qinbo Wang, Zhengwei Yuan   +7 more
doaj   +1 more source

TRIM4 is associated with neural tube defects based on genome-wide DNA methylation analysis

Clinical Epigenetics, 2019
Background Neural tube defects (NTDs) are complex abnormalities associated with gene-environment interactions. The underlying cause has not been determined. Methods Spinal cord tissues from cases with NTDs and healthy controls were collected. Methylation
Henan Zhang, Yi Guo, Hui Gu, Xiaowei Wei, Wei Ma, Dan Liu, Kun Yu, Wenting Luo, Ling Ma, Yusi Liu, Jia Xue, Jieting Huang, Yanfu Wang, Shanshan Jia, Naixuan Dong, Hongyan Wang, Zhengwei Yuan   +16 more
doaj   +1 more source

Automated prediction of early spontaneous miscarriage based on the analyzing ultrasonographic gestational sac imaging by the convolutional neural network: a case-control and cohort study

BMC Pregnancy and Childbirth, 2022
Background It is challenging to predict the outcome of the pregnancy when fetal heart activity is detected in early pregnancy. However, an accurate prediction is of importance for obstetricians as it helps to provide appropriate consultancy and determine
Yu Wang, Qixin Zhang, Chenghuan Yin, Lizhu Chen, Zeyu Yang, Shanshan Jia, Xue Sun, Yuzuo Bai, Fangfang Han, Zhengwei Yuan   +9 more
doaj   +1 more source

Congenital perineal hamartomas with rectal duplication: A case report

Frontiers in Medicine, 2023
BackgroundCongenital perineal hamartomas are rare, and reports of prenatal ultrasound diagnosis are limited. Perineal hamartomas are usually associated with other structural malformations, which complicate the therapeutic regime.Case presentationWe ...
Yixin Zhang, Mo Zhang, Wei Ma, Zhengwei Yuan, Dajia Wang, Lizhu Chen   +5 more
doaj   +1 more source

Key Modules and Hub Genes Identified by Coexpression Network Analysis for Revealing Novel Biomarkers for Spina Bifida

Frontiers in Genetics, 2020
Spina bifida is a common neural tube defect (NTD) accounting for 5–10% of perinatal mortalities. As a polygenic disease, spina bifida is caused by a combination of genetic and environmental factors, for which the precise molecular pathogenesis is still ...
Zijian Li, Zijian Li, Juan Feng, Zhengwei Yuan   +3 more
doaj   +1 more source

Severe Unilateral Microtia with Aural Atresia, Hair White Patch, Stereotypes in a Young Boy with De novo 16p13.11 Deletion: Reasons for a New Genotype–Phenotype Correlation

Global Medical Genetics, 2023
Background Microtia is an uncommon congenital malformation ranging from mild anatomic structural abnormalities to partial or complete absence of the ear leading to hearing impairment.
Piero Pavone, Xena Giada Pappalardo, Claudia Parano, Enrico Parano, Antonio Corsello, Martino Ruggieri, Giovanni Cacciaguerra, Raffaele Falsaperla   +7 more
doaj   +1 more source

Opioid exposure during pregnancy and the risk of congenital malformation: a meta-analysis of cohort studies

BMC Pregnancy and Childbirth, 2022
Background Opioid exposure during pregnancy has increased alarmingly in recent decades. However, the association between prenatal opioid exposure and congenital malformation risk has still been controversial.
Xinrui Wang, Yushu Wang, Borui Tang, Xin Feng   +3 more
doaj   +1 more source

Vestibular paroxysmia associated with congenital vascular malformation: A case report

Frontiers in Neuroscience, 2023
Vestibular paroxysmia (VP) is an uncommon paroxysmal disease, characterized by vertigo, tinnitus, and postural unsteadiness. The main reason of VP is neurovascular cross compression, while few cases of VP accompanied with congenital vascular malformation
Fei Liu, Zheng Zhang, Wan Wei, Lin Jiang
doaj   +1 more source

A rare Abernethy Ib malformation was initially misdiagnosed as chronic portal vein thrombosis in a 27-year-old female

Radiology Case Reports, 2022
Abernethy malformation or congenital portosystemic shunt is a rare congenital vascular malformation and anomaly of the splanchnic venous system defined by diverting portal blood away from the liver.
Mehrdad kayedi, MD, Behnam Kian, MD, Arash Teimouri, MD   +2 more
doaj   +1 more source

Comparative Study on the Differentiation of Mesenchymal Stem Cells between Fetal and Postnatal Rat Spinal Cord Niche

Cell Transplantation, 2016
In a previous study, we established a prenatal surgical approach and transplanted mesenchymal stem cells (MSCs) into the fetal rat spinal column to treat neural tube defects (NTDs).
Songying Cao, Xiaowei Wei, Hui Li, Jianing Miao, Guifeng Zhao, Di Wu, Bo Liu, Yi Zhang, Hui Gu, Lili Wang, Yang Fan, Dong An, Zhengwei Yuan   +12 more
doaj   +1 more source