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Establishment of a murine model of congenital toxoplasmosis and validation of a qPCR assay to assess the parasite load in maternal and fetal tissues [PDF]

open access: goldFrontiers in Microbiology, 2023
Toxoplasma gondii is the causative agent of toxoplasmosis, a disease that affects warm-blooded animals and one third of the human population worldwide.
Jéssica S. Souza   +7 more
doaj   +4 more sources

Maternal and congenital toxoplasmosis in Mayotte: Prevalence, incidence and management. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2023
BackgroundToxoplasmosis is an infection caused by an intracellular protozoan, Toxoplasma gondii. It is usually asymptomatic, but toxoplasmosis acquired during pregnancy can cause congenital toxoplasmosis, potentially resulting in fetal damage ...
Laure Kamus   +7 more
doaj   +2 more sources

Real-time PCR in the diagnosis of congenital toxoplasmosis [PDF]

open access: yesBrazilian Journal of Infectious Diseases, 2023
The diagnosis of congenital toxoplasmosis presents limitations and therefore new options are necessary. The analysis of amniotic fluid by real-time PCR has already proved effective for confirmation of fetal infection.
Bianca Balzano De La Fuente Villar   +7 more
doaj   +2 more sources

Early diagnosis of congenital toxoplasmosis in newborn infants using IgG subclasses against two Toxoplasma gondii recombinant proteins [PDF]

open access: diamondMemorias do Instituto Oswaldo Cruz, 2012
The aim of this work was to evaluate the utility of ELISA-based testing of total IgG (IgGt) antibodies and its subclasses (IgG1, IgG2, IgG3 and IgG4) against soluble (STAg) and recombinant (rSAG1 and rMIC3) antigens of Toxoplasma gondii for diagnosing ...
Carlos Henryque de Souza e Silva   +6 more
doaj   +2 more sources

Digital Narratives: The Impact of Instagram® on Mothers of Children with Congenital Toxoplasmosis [PDF]

open access: yesChildren
Background: Congenital toxoplasmosis leads to severe complications in childhood and presents significant global health challenges. In Brazil, the prevalence of toxoplasmosis during pregnancy and congenital cases ranges from 0.3 to 8 per 1000 live births.
Gabrielle Gonçalves Veloso   +11 more
doaj   +2 more sources

Microcephaly Resulting From Congenital Toxoplasmosis: What the Radiologist can Expect to See? A Case Report [PDF]

open access: yesRadiology Case Reports
Microcephaly is defined as an occipitofrontal head circumference two standard deviations (2SD) below average for age and sex, with severe microcephaly below three standard deviations (3SD).
Marrakchi Salma, MD   +5 more
doaj   +2 more sources

Congenital toxoplasmosis: an in-depth density-equalizing mapping analysis to explore its global research architecture [PDF]

open access: goldParasites & Vectors, 2015
Background Toxoplasmosis endangers the unborn child if its infectious agent - toxoplasma gondii - is transmitted transplacentally during pregnancy. Although this condition occurs in all parts of the world and represents a major public health burden, no ...
Dörthe Brüggmann   +4 more
doaj   +2 more sources

First description of congenital toxoplasmosis after maternal coinfection with Toxoplasma gondii and severe acute respiratory syndrome coronavirus 2: a case report [PDF]

open access: yesJournal of Medical Case Reports, 2023
Background Congenital toxoplasmosis can be associated with serious clinical consequences from fetus to adulthood. Hence, early detection is required to minimize severe sequelae through appropriate therapy.
Vu Thao-Vi Dao   +7 more
doaj   +2 more sources

Discrimination between patients with acquired toxoplasmosis and congenital toxoplasmosis on the basis of the immune response to parasite antigens [PDF]

open access: bronze, 2000
Many persons infected with Toxoplasma gondii develop ocular lesions, Immunologic parameters in the response to I gondii were evaluated in infected persons with and without ocular lesions and in noninfected controls.
Belfort, Rubens Junior   +8 more
core   +3 more sources

Congenital toxoplasmosis in infants from chronically infected mothers: report of two cases [PDF]

open access: yesRevista Paulista de Pediatria
Objective: To describe two severe cases of congenital toxoplasmosis in infants born to chronically infected mothers who did not receive education or information on the prevention of gestational toxoplasmosis during prenatal care.
Roberta Rassi Almeida   +2 more
doaj   +2 more sources

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