Results 91 to 100 of about 12,376 (221)

Congenital Zika syndrome, time to communicate experiences [PDF]

The Journal of Maternal-Fetal & Neonatal Medicine, 2018
On 15 December 2017 was published in the Morbidity and Mortality Weekly Report, the Zodiac study, the first experience in Brazil with children affected by the congenital zika syndrome, in this expe...
openaire   +2 more sources

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, Volume 8, Issue 12, December 2025.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source

Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses [PDF]

, 2017
The recent outbreak of infection with Zika virus (ZIKV; Flaviviridae) has attracted attention to this previously neglected mosquito-borne pathogen and the need for efficient therapies.
Donald, Claire L., Kohl, Alain, Merits, Andres, Royle, Jamie, Varjak, Margus   +4 more
core   +1 more source

Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]

, 2020
Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T, Fu, M, Griffin, GE, Hu, Q, Li, C, Li, M, Liu, Y, Ni, F, Wang, H, Zhang, D, Zhang, M, Zheng, Z   +11 more
core   +1 more source

Advanced Electrochemical Genosensor for Zika Virus Detection in Biological Samples Based on Cysteamine‐Graphene Quantum Dots Bilayer

Electroanalysis, Volume 37, Issue 12, December 2025.
An electrochemical biosensor for Zika virus (ZIKV) detection is described. A DNA probe was immobilized on a gold electrode. After hybridization with the target (ZIKV), safranin was used as an intercalating indicator. Detection was performed by differential pulse voltammetry (DPV), where the current signal increases with the target concentration.
Luiz F. G. Luz, Márcia M. C. N. Soares, Ana G. Brito‐Madurro, João M. Madurro   +3 more
wiley   +1 more source

Host and viral mechanisms of congenital Zika syndrome [PDF]

Virulence, 2019
In 2015-2016, in the Americas, and especially in northeast Brazil, a significant number of cases of microcephaly and other congenital brain abnormalities were linked with an outbreak of Zika virus (ZIKV) infection in pregnant women. While maternal symptoms of ZIKV are generally mild and self-limiting, clinical presentation in fetuses and newborns ...
Brooke Liang, José Paulo Guida, Maria Laura Costa, Indira U. Mysorekar   +3 more
openaire   +4 more sources

The TH1/TH2 Response Imbalance Zika Virus Pathogenesis: An Immunological Paradox

APMIS, Volume 133, Issue 12, December 2025.
ABSTRACT Since its identification in 1947 and its global emergence in the Americas decades later, the Zika virus (ZIKV) has proven to be a multifaceted challenge to public health. Among the many aspects that remain poorly understood, the complex immunological paradox between Th1 and Th2 responses stands out, playing a central role in the ...
Carla Menezes, Lívia Martins, Gustavo Ferro, Bernard Arnaud, Juarez Quaresma, Pedro Vasconcelos, Jorge Sousa   +6 more
wiley   +1 more source

Clinical Trials and Administration of Zika Virus Vaccine in Pregnant Women: Lessons (that Should Have Been) Learned from Excluding Immunization with the Ebola Vaccine during Pregnancy and Lactation

Vaccines, 2018
As evidenced from recent epidemics, both Ebola and Zika virus infection are potentially catastrophic when occurring in pregnant women. Ebola virus causes extremely high rates of mortality in both mothers and infants; Zika virus is a TORCH infection that ...
David A. Schwartz
doaj   +1 more source

Human Cytomegalovirus Associated Neuropathies: A Comprehensive Review From Pathophysiology to Clinical and Therapeutic Considerations

Journal of the Peripheral Nervous System, Volume 30, Issue 4, December 2025.
ABSTRACT Human cytomegalovirus (HCMV) is a neurotropic, double‐stranded DNA virus from the Herpesviridae family. It has a large genome, infects the majority of populations, and typically causes asymptomatic infections in healthy individuals. After the initial infection with established lifelong latency, HCMV can reactivate and cause disorders including
Naomi Behanan, Sarab Mohamed, Rhona Chen, Gloria Mak, Jian‐Qiang Lu   +4 more
wiley   +1 more source

Evidence of Abortion Attitude Flexibility during COVID‐19 in Pernambuco, Brazil

Studies in Family Planning, Volume 56, Issue 4, Page 755-777, December 2025.
Abstract This study examines changes in women's attitudes toward abortion in Brazil during the first year of the COVID‐19 pandemic, focusing on the role of religious affiliation. Brazil provides a unique context for examining abortion attitudes because of its strict abortion policies, changing religious landscape, and back‐to‐back Zika and COVID‐19 ...
Brooke Whitfield, Raquel Zanatta Coutinho, Leticia Marteleto   +2 more
wiley   +1 more source