Results 111 to 120 of about 98,881 (284)

Intra-amniotic Injection of Mouse Embryos

open access: yesBio-Protocol, 2018
Recent outbreaks of infectious neuro-developmental diseases such as congenital Zika syndrome - have led to a demand for prognosis data from animal models.
Liyuan Cui   +4 more
doaj   +1 more source

Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons [PDF]

open access: yes, 2016
published_or_final_versio
Au Yeung, KHR   +17 more
core   +1 more source

Neutrophils at the Maternal‐Fetal Interface: Agents of Protection or Destruction?

open access: yesAmerican Journal of Reproductive Immunology, Volume 94, Issue 5, November 2025.
ABSTRACT Neutrophils, traditionally recognized for their role in innate immunity, have emerged as a key cell population at the maternal‐fetal interface, during both uncomplicated and pathological pregnancies. Neutrophil effector functions, including phagocytosis, neutrophil extracellular trap formation, and degranulation, can play protective roles ...
Sallie L. Fell   +5 more
wiley   +1 more source

Risk Factors for Hearing Loss Are Comparable in Preterm Versus Term Children: A Systematic Review

open access: yesActa Paediatrica, Volume 114, Issue 11, Page 2763-2782, November 2025.
ABSTRACT Aim Hearing loss occurs more frequently in preterm children. However, the influence of prematurity itself is unclear. We examined whether risk factors for hearing loss differ between preterm and term infants. Methods We conducted a systematic search of three databases in March 2023 for studies comparing risk factors for hearing loss in preterm
Pauline Roehrs   +4 more
wiley   +1 more source

The Role of Amniocentesis in the Diagnosis of Congenital Zika Syndrome [PDF]

open access: yesClinical Infectious Diseases, 2019
Abstract There are limited data on amniocentesis as a diagnostic tool for congenital Zika syndrome. Here we report on a prospective cohort of 16 women with suspected Zika virus infection in a highly endemic area, and discuss the role of amniocentesis in the prenatal diagnosis of fetal Zika infection.
Jose Paulo Pereira   +9 more
openaire   +2 more sources

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, Volume 58, Issue 11, November 2025.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

Ocular Histopathologic Features of Congenital Zika Syndrome [PDF]

open access: yesJAMA Ophthalmology, 2017
Congenital Zika syndrome (CZS) is known to be associated with severe malformations in newborns. Although microcephaly is the hallmark of this disease, the ocular findings are important given the severe visual impairment that has been observed in these patients. Regardless of the increased number of CZS cases reported, to date, no studies have described
Maria P, Fernandez   +12 more
openaire   +2 more sources

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

open access: yesCell Proliferation, Volume 58, Issue 11, November 2025.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far   +4 more
wiley   +1 more source

Clinical Trials and Administration of Zika Virus Vaccine in Pregnant Women: Lessons (that Should Have Been) Learned from Excluding Immunization with the Ebola Vaccine during Pregnancy and Lactation

open access: yesVaccines, 2018
As evidenced from recent epidemics, both Ebola and Zika virus infection are potentially catastrophic when occurring in pregnant women. Ebola virus causes extremely high rates of mortality in both mothers and infants; Zika virus is a TORCH infection that ...
David A. Schwartz
doaj   +1 more source

Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography

open access: yesDevelopmental Medicine &Child Neurology, Volume 67, Issue 11, Page 1383-1408, November 2025.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16431 Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment.
Ana Alarcón   +33 more
wiley   +1 more source

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