Results 71 to 80 of about 12,376 (221)

Ocular Histopathologic Features of Congenital Zika Syndrome [PDF]

JAMA Ophthalmology, 2017
Congenital Zika syndrome (CZS) is known to be associated with severe malformations in newborns. Although microcephaly is the hallmark of this disease, the ocular findings are important given the severe visual impairment that has been observed in these patients. Regardless of the increased number of CZS cases reported, to date, no studies have described
Maria P, Fernandez, Edgar, Parra Saad, Martha, Ospina Martinez, Sheryl, Corchuelo, Marcela, Mercado Reyes, Maria Jose, Herrera, Miguel, Parra Saavedra, Angelica, Rico, Angela M, Fernandez, Richard K, Lee, Camila V, Ventura, Audina M, Berrocal, Sander R, Dubovy   +12 more
openaire   +2 more sources

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons [PDF]

, 2016
published_or_final_versio
Au Yeung, KHR, Cai, J, Chan, CS, Chan, JFW, Chan, KH, Chik, KKH, Jin, D, Kok, KH, Mak, WN, Poon, KM, Tee, KM, Tsang, OL, Yin, F, Yip, CY, Yuen, KY, Zhang, J, Zhu, H, Zhu, Z   +17 more
core   +1 more source

Mosquito‐Borne Viruses of Clinical Significance

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Mosquito‐borne viruses represent a significant public health concern globally, with rising incidence rates leading to increased morbidity and mortality. This review aims to synthesize current knowledge regarding mosquito‐borne viruses, focusing on their geographic distribution, clinical impact, diagnostic challenges, treatment ...
Donath Damian
wiley   +1 more source

Ocular abnormalities in congenital Zika syndrome: a case report, and review of the literature

Journal of Medical Case Reports, 2018
Background As the number of children with Zika virus-related complications grows, the long-term developmental trajectory and its effects on families are unknown.
Jade Gieseke Guevara, Swati Agarwal-Sinha   +1 more
doaj   +1 more source

Toward Dual‐Function Nanoparticle Platforms for Arboviral Diagnostics and Vaccines: Advances, Challenges, and Future Prospects

Nano Select, Volume 7, Issue 2, February 2026.
This review explores nanoparticle (NP)‐based biosensors and nanovaccine platforms for arboviral infections, highlighting their design, performance, and translational potential. By comparing case studies across viruses, it identifies gold‐standard nanomaterials such as gold NPs (AuNPs), zinc oxide NPs (ZnONPs), molybdenum disulfide (MoS2) nanocomposites,
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

Outbreak of Zika virus pathogenesis and quest of its vaccine development: Where do we stand now? [PDF]

, 2018
Zika virus (ZIKV) infection is a life-threatening tropical infection, mainly caused by mosquito bite. After a very long period of quietness, ZIKV infections have become a problematic issue again.
Aarti, Chirom, Aarti, Chirom, BARBABOSA PLIEGO, ALBERTO, BARBABOSA PLIEGO, ALBERTO, KHUSRO, AMEER, KHUSRO, AMEER, SANCHEZ APARICIO, PEDRO, SANCHEZ APARICIO, PEDRO   +7 more
core   +1 more source

The Creation of a Weight of Evidence Scoring Database for Risk Factors for Adverse Impacts to Birth Outcomes Using Expert Elicitation

Birth Defects Research, Volume 118, Issue 1, January 2026.
ABSTRACT Background Adverse birth outcomes are important public health measures and account for a substantial public health burden. There is considerable diversity of these health endpoints, as well as in the many factors suspected or recognized to increase their risk.
Paul J. Villeneuve, Ann Aschengrau, Michelle L. Bell, Yang Cao, Mark Elwood, Guy Eslick, Shelley Harris, Leeka Kheifets, Babak Khoshnood, Robert Norman, Nelson Pace, Johan Reutfors, Jeremy M. Schraw, Jose R. Suarez‐Lopez, Gunnar Toft, R. Douglas Wilson, Christopher R. Kirman, Tyler Carneal, Sean M. Hays   +18 more
wiley   +1 more source

Mathematical modeling of Zika disease in pregnant women and newborns with microcephaly in Brazil

, 2017
We propose a new mathematical model for the spread of Zika virus. Special attention is paid to the transmission of microcephaly. Numerical simulations show the accuracy of the model with respect to the Zika outbreak occurred in Brazil.Comment: This is a ...
Area, Ivan, Ndairou, Faical, Nieto, Juan J., Silva, Cristiana J., Torres, Delfim F. M.   +4 more
core   +1 more source

Bioactivity‐Guided Isolation of β‐Sitosterol From Terminalia glabrescens as a Potent Anti‐Zika Virus Agent

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Zika virus (ZIKV) infection remains a global health concern due to its neurological complications and the lack of specific drugs or vaccines. This study investigated the anti‐ZIKV potential of an ethanolic extract from Terminalia glabrescens leaves.
Rosângela Santos Pereira, Priscilla Rodrigues Valadares Campana, Vivian Vasconcelos Costa, Vinícius Gonçalves Maltarollo, Rodrigo Maia de Pádua, José Hugo Sousa de Gomes, Grasiely Farias de Sousa, José Dias de Souza Filho, Daniele da Glória de Souza, Mauro Martins Teixeira, Fernão Castro Braga   +10 more
wiley   +1 more source