Results 81 to 90 of about 98,881 (284)

ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas. [PDF]

open access: yes, 2019
Zika Preparedness Latin American Network (ZikaPLAN) is a research consortium funded by the European Commission to address the research gaps in combating Zika and to establish a sustainable network with research capacity building in the Americas.
Alessandro Sette   +53 more
core   +9 more sources

Host and viral mechanisms of congenital Zika syndrome [PDF]

open access: yesVirulence, 2019
In 2015-2016, in the Americas, and especially in northeast Brazil, a significant number of cases of microcephaly and other congenital brain abnormalities were linked with an outbreak of Zika virus (ZIKV) infection in pregnant women. While maternal symptoms of ZIKV are generally mild and self-limiting, clinical presentation in fetuses and newborns ...
Brooke Liang   +3 more
openaire   +4 more sources

Health needs of mothers of children with Congenital Zika Syndrome: an integrative review.

open access: yesRevista Brasileira de Enfermagem, 2022
OBJECTIVES to evidence and analyze the health needs of mothers of children with Congenital Zika Syndrome. METHODS a total of 44 articles published between October/2015 and March/2021 on PubMed, LILACS, Scopus, Web of Science and Science Direct were ...
P. Vale   +5 more
semanticscholar   +1 more source

The Zika Virus Epidemic in Brazil: From Discovery to Future Implications. [PDF]

open access: yes, 2018
The first confirmed case of Zika virus infection in the Americas was reported in Northeast Brazil in May 2015, although phylogenetic studies indicate virus introduction as early as 2013.
Banks   +13 more
core   +3 more sources

Zika Virus Infection during Pregnancy and Effects on Early Childhood Development, French Polynesia, 2013–2016

open access: yesEmerging Infectious Diseases, 2018
Congenital Zika virus syndrome consists of a large spectrum of neurologic abnormalities seen in infants infected with Zika virus in utero. However, little is known about the effects of Zika virus intrauterine infection on the neurocognitive development ...
Lorenzo Subissi   +17 more
doaj   +1 more source

Mitigating the risk of Zika virus contamination of raw materials and cell lines in the manufacture of biologicals [PDF]

open access: yes, 2018
Ensuring the virological safety of biologicals is challenging due to the risk of viral contamination of raw materials and cell banks, and exposure during in-process handling to known and/or emerging viral pathogens.
Armstrong, Alison A.   +6 more
core   +1 more source

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki   +3 more
wiley   +1 more source

Clinical findings in congenital infection by Zika virus: a retrospective study in a reference hospital in Central-West Brazil

open access: yesBMC Pediatrics, 2019
Background An increased number of congenital Zika virus infections with neurological and musculoskeletal malformations have been diagnosed worldwide, however, there are still several gaps in the knowledge about this infection, its associated mechanism ...
Cláudia de Paula Guimarães   +5 more
doaj   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

[Primary care in the context of the Zika epidemic and congenital Zika syndrome in the state of Pernambuco, Brazil: context, bond and care].

open access: yesCiência & Saúde Coletiva, 2022
The Zika epidemic brought to the fore the birth of children with unknown and unexpected needs that demand longitudinal follow-up, strengthening the bond, comprehensiveness and coordination of care in health, which are essential attributes of primary ...
Bernadete Perez Coêlho   +4 more
semanticscholar   +1 more source

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