A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source
Research of Integrated Congestion Control Mechanism
In order to solve the problem that classifying mechanism of SFB congestion control algorithm for wireless sensor network could be influenced to cause transmission performance degradation of TCP flow under large network flow, the paper introduced ...
LAI Cheng-yu
doaj
A General and Efficient Framework for the Rapid Design of Miniaturized, Wideband, and High‐Bit RIS
A general and efficient framework is proposed for the rapid design of high‐performance reconfigurable intelligent surfaces (RISs). This framework integrates advanced antenna design techniques and incorporates various load types, quantities, and values to achieve the design of high‐performance RISs.
Jun Wei Zhang +14 more
wiley +1 more source
Feedback-Based Control Loop Congestion Control Algorithm for Wireless Networks
Wi-Fi plays a crucial role in connecting private professional networks by providing varying data rates based on channel quality. Despite advancements in Wi-Fi protocols, there is still a problem of throughput degradation for higher data rate devices when
Ramyashree Venkatesh Bhat +3 more
doaj +1 more source
Optimization of BBR Congestion Control Algorithm Based on Pacing Gain Model. [PDF]
Yang S +5 more
europepmc +1 more source
In dynamic driving scenarios, the proposed approach ensures only temporally aligned sensor inputs to make driving decisions, preventing false activations. By enabling selective hardware‐level learning, it achieves fast, reliable responses under noisy conditions.
Kapil Bhardwaj +4 more
wiley +1 more source
Experimental Analysis and Optimization Approach of Self-Clocked Rate Adaptation for Multimedia Congestion Control Algorithm in Emulated 5G Environment. [PDF]
Zubaydi HD, Jagmagji AS, Molnár S.
europepmc +1 more source
The Geography of Success: A Spatial Analysis of Export Intensity in the Italian Wine Industry
ABSTRACT This paper investigates the paradox of how Italy's fragmented, SME‐dominated wine industry achieves global export success. Moving beyond purely firm‐centric explanations, we test whether export intensity is spatially dependent, clustering geographically in regional ecosystems.
Nicolas Depetris Chauvin, Jonas Di Vita
wiley +1 more source
PBQ-Enhanced QUIC: QUIC with Deep Reinforcement Learning Congestion Control Mechanism. [PDF]
Zhang Z +5 more
europepmc +1 more source
When the River Runs Low: Heterogeneous Impacts of Transportation Disruptions on Local Grain Basis
ABSTRACT A substantial share of U.S. soybean and corn exports from the Midwest moves by barge along the Mississippi River system to export terminals in the Louisiana Gulf. Transportation costs between Midwestern grain elevators and export terminals create a wedge between prices at these locations, and shocks to these costs are partially passed on to ...
Yuan Zhang +3 more
wiley +1 more source

