Results 31 to 40 of about 15,658 (294)

Consistent estimation in an implicit quadratic measurement error model

open access: yes, 2004
An adjusted least squares estimator is derived that yields a consistent estimate of the parameters of an implicit quadratic measurement error model. In addition, a consistent estimator for the measurement error noise variance is proposed.
Er Kukush   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Disjunctive cuts in Mixed-Integer Conic Optimization [PDF]

open access: yes, 2022
This paper studies disjunctive cutting planes in Mixed-Integer Conic Programming. Building on conic duality, we formulate a cut-generating conic program for separating disjunctive cuts, and investigate the impact of the normalization condition on its ...
Lodi A., Vielma J. -P., Tanneau M.
core   +2 more sources

A novel camera calibration method for fish-eye lenses using line features [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2014
In this paper, a novel method for the fish-eye lens calibration is presented. The method required only a 2D calibration plane containing straight lines i.e., checker board pattern without a priori knowing the poses of camera with respect to the ...
P. Srestasathiern, N. Soontranon
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Graphical Multiplication Using Straightedge When a Conic Is Given (A Generalization of Möbius’s Observation)

open access: yesMathematics
Around 1840, A.F. Möbius discovered a remarkable property of the parabola: the curve drawn in the Cartesian coordinate system can be used to graphically multiply any integers.
Jiří Blažek, Josef Blažek
doaj   +1 more source

Birational Geometry of 3-fold Mori Fibre Spaces [PDF]

open access: yes, 2004
We study the geography and birational geometry of 3-fold conic bundles over P\(^2\) and cubic del Pezzo fibrations over P\(^1\).
Brown, G., Corti, A., Zucconi, F.
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

REMARKS ON LIPSCHITZ GEOMETRY OF GLOBALLY CONIC SINGULAR MANIFOLDS

open access: yesTạp chí Khoa học Đại học Đà Lạt
We study metric properties of manifolds with conic singularities and present a natural interplay between metrically conic and metrically asymptotically conic behavior.
André Costa   +2 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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