Results 21 to 30 of about 621 (88)

A Conserved Magnaporthe oryzae Effector Counteracts the Rice Ubiquitin‐Proteasome System by Disrupting the E2 Function to Suppress Immunity

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 4302-4316, June 2026.
ABSTRACT Pathogens commonly secrete effectors into host cells to facilitate invasion. In the host ubiquitin‐proteasome system (UPS), E3 ubiquitin ligases often target pathogen effectors for degradation, thereby enhancing immune responses. In turn, pathogen effectors frequently disrupt E3 ligase function to promote virulence. However, it remains largely
Min Wang   +19 more
wiley   +1 more source

The Basic Helix–Loop–Helix Transcription Factors UvBhlh1 and UvBhlh6 Coordinate Virulence in the Rice False Smut Fungus Ustilaginoidea virens

open access: yesMolecular Plant Pathology, Volume 27, Issue 5, May 2026.
Transcription factors UvBhlh1 and UvBhlh6 are essential for early infection and virulence in Ustilaginoidea virens. These two proteins form a heterodimer that cooperatively regulates downstream target genes during pathogenesis. ABSTRACT Ustilaginoidea virens is the causal agent of rice false smut, a devastating and globally widespread fungal disease ...
Huijuan Cao   +11 more
wiley   +1 more source

The Fusarium sacchari Effector FsP4H1 Targets the Transcription Factor DPb to Disrupt Catalase‐Mediated H2O2 Homeostasis and Suppress Host Immunity

open access: yesMolecular Plant Pathology, Volume 27, Issue 5, May 2026.
FsP4H1 interacts with the transcription factor DPb, a positive regulator of plant immunity, and facilitates its degradation via the 26S proteasome. This degradation leads to downregulation of catalase genes ScCAT9, ScCAT34 or NbCAT to enhance host susceptibility. ABSTRACT Pokkah boeng disease has been reported in nearly all countries where sugarcane is
Qianqian Ren   +7 more
wiley   +1 more source

ERAD Component MoHrd3 Facilitates Pathogenicity and Establishes a Direct Regulation on Autophagy in Magnaporthe Oryzae

open access: yesAdvanced Science, Volume 13, Issue 24, 27 April 2026.
MoHrd3 plays a crucial role in regulating the pathogenicity of Magnaporthe oryzae. As an ER‐associated degradation component, MoHrd3 involves in ER stress‐triggered autophagy. It facilitates the fusion between the autophagosome and the vacuole via enhancing the interaction between MoAtg8 and MoYpt7.
Huiqing Xia   +11 more
wiley   +1 more source

Glutathione Impacts Both Batrachochytrium dendrobatidis Virulence and Amphibian Cellular Defense in a Chytridiomycosis Model

open access: yesMicrobiologyOpen, Volume 15, Issue 2, April 2026.
Glutathione shapes interactions between Batrachochytrium dendrobatidis (Bd) and amphibian hosts. In Bd, glutathione reductase is essential for survival, and exogenous glutathione enhances zoospore release. In host cells, Bd infection depletes glutathione and increases oxidative stress.
Rebecca J. Webb   +4 more
wiley   +1 more source

Fungus Derived Indole‐3‐Acetic Acid Controls Developmental Conidial Death in Magnaporthe oryzae

open access: yesMolecular Plant Pathology, Volume 27, Issue 4, April 2026.
The severity of rice blast disease, caused by the fungus Magnaporthe oryzae, is influenced by IAA concentration and cell density. IAA regulates ferroptotic death of the developing conidia by affecting iron and lipid homeostasis. ABSTRACT Ferroptotic death of the developing conidia is important for pathogenicity of the blast fungus Magnaporthe oryzae ...
Yuming Ma   +7 more
wiley   +1 more source

Sugar sensing and regulation of conidiation in Neurospora crassa [PDF]

open access: yes, 2004
The orange bread mold Neurospora crassa is a useful model for the study of filamentous fungi. One of the asexual reproduction cycles in N. crassa, macroconidiation, can be induced by several environmental cues, including glucose starvation.
Xie, Xin
core  

A Pangenome Framework Reveals Conserved Pathogenicity‐Associated Biosynthetic Gene Clusters in Fusarium equiseti, a Root Rot Pathogen of Panax notoginseng

open access: yesMolecular Plant Pathology, Volume 27, Issue 4, April 2026.
Integrating pangenome and infection‐stage transcriptome analyses with CRISPR/Cas9 genetics identifies conserved secondary metabolite biosynthetic gene clusters, including an ICS–NRPS and a siderophore pathway, as key determinants of Fusarium equiseti P26 pathogenicity on Panax notoginseng.
Xuping Zhang   +4 more
wiley   +1 more source

Pan2‐Pan3 Complex‐Mediated Deadenylation Enforces mRNA Quality Control for Infection of the Rice Blast Fungus

open access: yesAdvanced Science, Volume 13, Issue 18, 27 March 2026.
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv   +6 more
wiley   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song   +14 more
wiley   +1 more source

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