Results 21 to 30 of about 621 (88)
ABSTRACT Pathogens commonly secrete effectors into host cells to facilitate invasion. In the host ubiquitin‐proteasome system (UPS), E3 ubiquitin ligases often target pathogen effectors for degradation, thereby enhancing immune responses. In turn, pathogen effectors frequently disrupt E3 ligase function to promote virulence. However, it remains largely
Min Wang +19 more
wiley +1 more source
Transcription factors UvBhlh1 and UvBhlh6 are essential for early infection and virulence in Ustilaginoidea virens. These two proteins form a heterodimer that cooperatively regulates downstream target genes during pathogenesis. ABSTRACT Ustilaginoidea virens is the causal agent of rice false smut, a devastating and globally widespread fungal disease ...
Huijuan Cao +11 more
wiley +1 more source
FsP4H1 interacts with the transcription factor DPb, a positive regulator of plant immunity, and facilitates its degradation via the 26S proteasome. This degradation leads to downregulation of catalase genes ScCAT9, ScCAT34 or NbCAT to enhance host susceptibility. ABSTRACT Pokkah boeng disease has been reported in nearly all countries where sugarcane is
Qianqian Ren +7 more
wiley +1 more source
MoHrd3 plays a crucial role in regulating the pathogenicity of Magnaporthe oryzae. As an ER‐associated degradation component, MoHrd3 involves in ER stress‐triggered autophagy. It facilitates the fusion between the autophagosome and the vacuole via enhancing the interaction between MoAtg8 and MoYpt7.
Huiqing Xia +11 more
wiley +1 more source
Glutathione shapes interactions between Batrachochytrium dendrobatidis (Bd) and amphibian hosts. In Bd, glutathione reductase is essential for survival, and exogenous glutathione enhances zoospore release. In host cells, Bd infection depletes glutathione and increases oxidative stress.
Rebecca J. Webb +4 more
wiley +1 more source
Fungus Derived Indole‐3‐Acetic Acid Controls Developmental Conidial Death in Magnaporthe oryzae
The severity of rice blast disease, caused by the fungus Magnaporthe oryzae, is influenced by IAA concentration and cell density. IAA regulates ferroptotic death of the developing conidia by affecting iron and lipid homeostasis. ABSTRACT Ferroptotic death of the developing conidia is important for pathogenicity of the blast fungus Magnaporthe oryzae ...
Yuming Ma +7 more
wiley +1 more source
Sugar sensing and regulation of conidiation in Neurospora crassa [PDF]
The orange bread mold Neurospora crassa is a useful model for the study of filamentous fungi. One of the asexual reproduction cycles in N. crassa, macroconidiation, can be induced by several environmental cues, including glucose starvation.
Xie, Xin
core
Integrating pangenome and infection‐stage transcriptome analyses with CRISPR/Cas9 genetics identifies conserved secondary metabolite biosynthetic gene clusters, including an ICS–NRPS and a siderophore pathway, as key determinants of Fusarium equiseti P26 pathogenicity on Panax notoginseng.
Xuping Zhang +4 more
wiley +1 more source
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv +6 more
wiley +1 more source
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song +14 more
wiley +1 more source

