Results 1 to 10 of about 7,107,261 (334)

High hydrostatic pressure harnesses the biosynthesis of secondary metabolites via the regulation of polyketide synthesis genes of hadal sediment-derived fungi

Frontiers in Microbiology, 2023
Deep-sea fungi have evolved extreme environmental adaptation and possess huge biosynthetic potential of bioactive compounds. However, not much is known about the biosynthesis and regulation of secondary metabolites of deep-sea fungi under extreme ...
Ludan Deng, Maosheng Zhong, Yongqi Li, Guangzhao Hu, Changhao Zhang, Qingqing Peng, Zhizhen Zhang, Jiasong Fang, Xi Yu   +8 more
doaj   +1 more source

Chromatin-Mediated Regulation of Genome Plasticity in Human Fungal Pathogens

Genes, 2019
Human fungal pathogens, such as Candida albicans, Aspergillus fumigatus and Cryptococcus neoformans, are a public health problem, causing millions of infections and killing almost half a million people annually. The ability of these pathogens to colonise
A. Buscaino
semanticscholar   +1 more source

Transcriptome analysis of silkworm, Bombyx mori, during early response to Beauveria bassiana challenges. [PDF]

PLoS ONE, 2014
Host-pathogen interactions are complex processes and it is a central challenge to reveal these interactions. Fungal infection of silkworm, Bombyx mori, may induce a variety of responsive reaction. However, little is known about the molecular mechanism of
Chengxiang Hou, Guangxing Qin, Ting Liu, Tao Geng, Kun Gao, Zhonghua Pan, Heying Qian, Xijie Guo   +7 more
doaj   +1 more source

Complex epigenetic regulation of alkaloid biosynthesis and host interaction by heterochromatin protein I in a fungal endophyte-plant symbiosis.

Fungal Genetics and Biology, 2019
Epichloë festucae forms mutualistic symbiotic interactions with grasses of the Lolium and Festuca genera. Protection from insect and mammalian herbivory are the best-documented host benefits of these associations.
Tetsuya Chujo, Yonathan Lukito, Carla J. Eaton, P. Dupont, L. Johnson, David J. Winter, M. Cox, B. Scott   +7 more
semanticscholar   +1 more source

The consciousness of stress: Functional roles of ORFs and MicroRNAs in tomato defense against fungal pathogens

Plant Stress
Tomato plants constantly encounter fungal pathogens, which trigger intricate defense mechanisms at the molecular level. Among these, upstream open reading frames (uORFs) and main open reading frames (mORFs), together with microRNAs (miRNAs), play pivotal
Misbah Naz, Zhibing Rui, Haowen Ni, Muhammad Rahil Afzal, Zhuo Chen   +4 more
doaj   +1 more source

MicroRNA Regulation of Host Immune Responses following Fungal Exposure

Frontiers in Immunology, 2018
Fungal bioaerosols are ubiquitous in the environment and human exposure can result in a variety of health effects ranging from systemic, subcutaneous, and cutaneous infections to respiratory morbidity including allergy, asthma, and hypersensitivity ...
T. Croston, A. Lemons, D. Beezhold, B. Green   +3 more
semanticscholar   +1 more source

Streptomyces roseolus, A Promising Biocontrol Agent Against Aspergillus flavus, the Main Aflatoxin B₁ Producer

Toxins, 2018
Crop contamination by aflatoxin B1 is a current problem in tropical and subtropical regions. In the future, this contamination risk may be expanded to European countries due to climate change.
Isaura Caceres, Selma P. Snini, Olivier Puel, Florence Mathieu   +3 more
doaj   +1 more source

Translational Regulation Promotes Oxidative Stress Resistance in the Human Fungal Pathogen Cryptococcus neoformans

mBio, 2019
Fungal survival in a mammalian host requires the coordinated expression and downregulation of a large cohort of genes in response to cellular stresses. Initial infection with C.
Jay Leipheimer, A. L. Bloom, C. Campomizzi, Yana Salei, J. Panepinto   +4 more
semanticscholar   +1 more source

Chromatin Structure and Drug Resistance in Candida spp.

Journal of Fungi, 2020
Anti-microbial resistance (AMR) is currently one of the most serious threats to global human health and, appropriately, research to tackle AMR garnishes significant investment and extensive attention from the scientific community.
Callum J. O’Kane, Rachel Weild, Edel M. Hyland   +2 more
doaj   +1 more source

Regulation of antimicrobial peptide gene expression by nutrients and by-products of microbial metabolism

European Journal of Nutrition, 2012
BackgroundAntimicrobial peptides (AMPs) are synthesized and secreted by immune and epithelial cells that are constantly exposed to environmental microbes.
Yan Campbell, Mary L. Fantacone, A. Gombart   +2 more
semanticscholar   +1 more source