The COMPASS‐like complex modulates fungal development and pathogenesis by regulating H3K4me3‐mediated targeted gene expression in Magnaporthe oryzae [PDF]
Abstract Histone‐3‐lysine‐4 (H3K4) methylation is catalysed by the multiprotein complex known as the Set1/COMPASS or MLL/COMPASS‐like complex, an element that is highly evolutionarily conserved from yeast to humans.
Sida Zhou +10 more
openaire +3 more sources
Regulation of gene expression by the action of a fungal lncRNA on a transactivator [PDF]
Long non-coding RNAs (lncRNAs) are crucial factors acting on regulatory processes in eukaryotes. Recently, for the first time in a filamentous fungus, the lncRNA HAX1 was characterized in the ascomycete Trichoderma reesei. In industry, this fungus is widely applied for the high-yield production of cellulases.
Petra Till +5 more
openaire +2 more sources
Doxycycline-regulated gene expression in the opportunistic fungal pathogen Aspergillus fumigatus [PDF]
Abstract Background Although Aspergillus fumigatus is an important human fungal pathogen there are few expression systems available to study the contribution of specific genes to the growth and virulence of this opportunistic mould.
Askew David S +3 more
openaire +3 more sources
Light-regulated promoters for tunable, temporal, and affordable control of fungal gene expression [PDF]
Regulatable promoters are important genetic tools, particularly for assigning function to essential and redundant genes. They can also be used to control the expression of enzymes that influence metabolic flux or protein secretion, thereby optimizing product yield in bioindustry.
Kevin K. Fuller +2 more
openaire +2 more sources
MicroRNA-mediated regulation of gene expression in the response of rice plants to fungal elicitors [PDF]
MicroRNAs (miRNAs) are small non-coding RNAs that have important regulatory functions in plant growth, development, and response to abiotic stress. Increasing evidence also supports that plant miRNAs contribute to immune responses to pathogens. Here, we used deep sequencing of small RNA libraries for global identification of rice miRNAs that are ...
Baldrich, Patricia +5 more
openaire +4 more sources
pH regulation is a major determinant in expression of a fungal penicillin biosynthetic gene. [PDF]
Transcription of the ipnA gene encoding isopenicillin N synthetase, an enzyme of secondary metabolism, is under the control of the pH regulatory system in the fungus Aspergillus nidulans. External alkaline pH or mutations in pacC, the wide domain regulatory gene which mediates pH regulation, override carbon regulation of ipnA transcript levels ...
E A, Espeso +3 more
openaire +2 more sources
DNA-Demethylase Regulated Genes Show Methylation-Independent Spatiotemporal Expression Patterns
Recent research has indicated that a subset of defense-related genes is downregulated in the Arabidopsis DNA demethylase triple mutant rdd (ros1 dml2 dml3) resulting in increased susceptibility to the fungal pathogen Fusarium oxysporum.
Ulrike Schumann +4 more
doaj +1 more source
Rhamnolipids inhibit aflatoxins production in Aspergillus flavus by causing structural damages in the fungal hyphae and down-regulating the expression of their biosynthetic genes [PDF]
Aflatoxins are hepatotoxic and carcinogenic fungal secondary metabolites that usually contaminate crops and represent a serious health hazard for humans and animals worldwide. In this work, the effect of rhamnolipids (RLs) produced by Pseudomonas aeruginosa #112 on the growth and aflatoxins production by Aspergillus flavus MUM 17.14 was studied in ...
Rodrigues, Ana Isabel Geraldes +6 more
openaire +3 more sources
Nutritional immunity is a process whereby an infected host manipulates essential micronutrients to defend against an invading pathogen. We reveal a dynamic aspect of nutritional immunity during infection that involves copper assimilation.
Joanna Mackie +7 more
doaj +1 more source
Fungal infections are a major global health burden where Candida albicans is among the most common fungal pathogen in humans and is a common cause of invasive candidiasis.
Christian H. Luther +6 more
doaj +1 more source

