Results 1 to 10 of about 1,470,980 (359)

Methods of conjugate gradients for solving linear systems

open access: bronze, 1952
An iterative algorithm is given for solving a system Ax=k of n linear equations in n unknowns. The solution is given in n steps. It is shown that this method is a special case of a very general method which also includes Gaussian elimination.
Magnus R. Hestenes, Eduard Stiefel
openalex   +2 more sources

New modification of the hestenes-stiefel with strong wolfe line search [PDF]

open access: yes, 2021
. The method of the nonlinear conjugate gradient is widely used in solving large-scale unconstrained optimization since been proven in solving optimization problems without using large memory storage.
Basri, Srimazzura   +2 more
core   +1 more source

Antibody drug conjugate: the “biological missile” for targeted cancer therapy

open access: yesSignal Transduction and Targeted Therapy, 2022
Antibody–drug conjugate (ADC) is typically composed of a monoclonal antibody (mAbs) covalently attached to a cytotoxic drug via a chemical linker. It combines both the advantages of highly specific targeting ability and highly potent killing effect to ...
Zhiwen Fu   +4 more
semanticscholar   +1 more source

CONJUGATE NATURAL CONVECTION IN A POROUS ENCLOSURE SANDWICHED BY FINITE WALLS AND SUBJECTED TO CONVECTION COOLING CONDITION

open access: yesJournal of Engineering and Sustainable Development, 2021
Steady conjugate natural convection heat transfer in a two-dimensional enclosure filled with fluid saturated porous medium is studied numerically. The two vertical boundaries of the enclosure are kept isothermally at same temperature, the horizontal ...
Hassan H. Hatem, Luma F. Ali
doaj   +1 more source

Conjugation spaces [PDF]

open access: yesAlgebraic & Geometric Topology, 2005
There are classical examples of spaces X with an involution tau whose mod 2-comhomology ring resembles that of their fixed point set X^tau: there is a ring isomorphism kappa: H^2*(X) --> H^*(X^tau). Such examples include complex Grassmannians, toric manifolds, polygon spaces.
Hausmann, Jean-Claude   +2 more
openaire   +4 more sources

Novel G‐CSF conjugated anionic globular dendrimer: Preparation and biological activity assessment

open access: yesPharmacology Research & Perspectives, 2021
The most crucial role of granulocyte colony‐stimulating factor (G‐CSF) in the body is to increase the strength of immune system. In recent years, research on the use of nanoparticles in pharmaceuticals has been considered, most of which have been for ...
Seyed Shahaboddin Mousavi Motlagh   +7 more
doaj   +1 more source

Types of Conjugal Networks, Conjugal Conflict and Conjugal Quality [PDF]

open access: yesEuropean Sociological Review, 2004
This article considers how various configurations of network characteristics affect conjugal quality. To investigate this issue, we use data from a large survey on conjugal functioning, based on 910 married couples with co-resident children living in Switzerland. Using reports from both male and female partners, we first empirically define six types of
Widmer, Eric   +2 more
openaire   +3 more sources

On-demand biomanufacturing of protective conjugate vaccines

open access: yesScience Advances, 2021
In vitro conjugate vaccine expression technology enables rapid and portable biosynthesis of protective antibacterial vaccines. Conjugate vaccines are among the most effective methods for preventing bacterial infections.
Jessica C. Stark   +12 more
semanticscholar   +1 more source

Polysaccharide dextran-based conjugate for selective co-delivery of two synergistic drugs docetaxel and docosahexaenoic acid to tumor cells

open access: yesDrug Delivery, 2023
Most chemotherapeutic agents are nonspecific distribution and cause systemic toxicities. Polysaccharide-based conjugates are promising strategies to overcome these drawbacks.
Peng Dong   +8 more
doaj   +1 more source

Development of Phosphoramidite Reagents for the Synthesis of Base-Labile Oligonucleotides Modified with a Linear Aminoalkyl and Amino-PEG Linker at the 3′-End

open access: yesMolecules, 2022
Oligonucleotides with an amino linker at the 3′-end are useful for the preparation of conjugated oligonucleotides. However, chemically modified nucleosides, which are unstable under basic conditions, cannot be incorporated into oligonucleotides using the
Takashi Osawa, Qin Ren, Satoshi Obika
doaj   +1 more source

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