Results 1 to 10 of about 1,051,691 (340)
New modification of the hestenes-stiefel with strong wolfe line search [PDF]
, 2021 . The method of the nonlinear conjugate gradient is widely used in solving large-scale unconstrained optimization since been proven in solving optimization problems without using large memory storage.
Basri, Srimazzura +2 more
core +1 more source
Algebraic & Geometric Topology, 2005 There are classical examples of spaces X with an involution tau whose mod 2-comhomology ring resembles that of their fixed point set X^tau: there is a ring isomorphism kappa: H^2*(X) --> H^*(X^tau). Such examples include complex Grassmannians, toric manifolds, polygon spaces.
Hausmann, Jean-Claude +2 more
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Types of Conjugal Networks, Conjugal Conflict and Conjugal Quality [PDF]
European Sociological Review, 2004 This article considers how various configurations of network characteristics affect conjugal quality. To investigate this issue, we use data from a large survey on conjugal functioning, based on 910 married couples with co-resident children living in Switzerland. Using reports from both male and female partners, we first empirically define six types of
Widmer, Eric +2 more
openaire +3 more sources
Pharmacokinetics of Pullulan–Dexamethasone Conjugates in Retinal Drug Delivery
Pharmaceutics, 2021 The treatment of retinal diseases by intravitreal injections requires frequent administration unless drug delivery systems with long retention and controlled release are used.
Eva Kicková +13 more
doaj +1 more source
Twenty Years of Research on Cyclodextrin Conjugates with PAMAM Dendrimers
Pharmaceutics, 2021 Recently, the number of gene and oligonucleotide drugs are increasing. Of various drug delivery systems (DDSs) for gene and oligonucleotide drugs, few examples of the clinical application of polymer as drug carriers are known, despite development of the ...
Hidetoshi Arima
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Molecules, 2023 In the search for crop protectants, amino acid ester conjugates have been widely investigated as potential antifungal agents. In this study, a series of rhein–amino acid ester conjugates were designed and synthesized in good yields, and their structures ...
Shunshun Chen +8 more
doaj +1 more source
Novel G‐CSF conjugated anionic globular dendrimer: Preparation and biological activity assessment
Pharmacology Research & Perspectives, 2021 The most crucial role of granulocyte colony‐stimulating factor (G‐CSF) in the body is to increase the strength of immune system. In recent years, research on the use of nanoparticles in pharmaceuticals has been considered, most of which have been for ...
Seyed Shahaboddin Mousavi Motlagh +7 more
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Molecules, 2022 Oligonucleotides with an amino linker at the 3′-end are useful for the preparation of conjugated oligonucleotides. However, chemically modified nucleosides, which are unstable under basic conditions, cannot be incorporated into oligonucleotides using the
Takashi Osawa, Qin Ren, Satoshi Obika
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Conjugated Bis(triarylboranes) with Disconnected Conjugation [PDF]
Zeitschrift für anorganische und allgemeine Chemie, 2021 AbstractA series of methylene‐bridged bis(triarylboranes) has been synthesized via two complementary routes using metal‐free catalytic Si/B exchange condensation under mild conditions. The title compounds comprise two borane moieties that show effective internal π‐conjugation involving the respective boron centers and the adjacent hetaryl groups ...
Nicolas Alexander Riensch +5 more
openaire +3 more sources
Drug Delivery, 2023 Most chemotherapeutic agents are nonspecific distribution and cause systemic toxicities. Polysaccharide-based conjugates are promising strategies to overcome these drawbacks.
Peng Dong +8 more
doaj +1 more source