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Methods of conjugate gradients for solving linear systems
An iterative algorithm is given for solving a system Ax=k of n linear equations in n unknowns. The solution is given in n steps. It is shown that this method is a special case of a very general method which also includes Gaussian elimination.
Magnus R. Hestenes, Eduard Stiefel
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New modification of the hestenes-stiefel with strong wolfe line search [PDF]
. The method of the nonlinear conjugate gradient is widely used in solving large-scale unconstrained optimization since been proven in solving optimization problems without using large memory storage.
Basri, Srimazzura+2 more
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Antibody drug conjugate: the “biological missile” for targeted cancer therapy
Antibody–drug conjugate (ADC) is typically composed of a monoclonal antibody (mAbs) covalently attached to a cytotoxic drug via a chemical linker. It combines both the advantages of highly specific targeting ability and highly potent killing effect to ...
Zhiwen Fu+4 more
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Steady conjugate natural convection heat transfer in a two-dimensional enclosure filled with fluid saturated porous medium is studied numerically. The two vertical boundaries of the enclosure are kept isothermally at same temperature, the horizontal ...
Hassan H. Hatem, Luma F. Ali
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There are classical examples of spaces X with an involution tau whose mod 2-comhomology ring resembles that of their fixed point set X^tau: there is a ring isomorphism kappa: H^2*(X) --> H^*(X^tau). Such examples include complex Grassmannians, toric manifolds, polygon spaces.
Hausmann, Jean-Claude+2 more
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Novel G‐CSF conjugated anionic globular dendrimer: Preparation and biological activity assessment
The most crucial role of granulocyte colony‐stimulating factor (G‐CSF) in the body is to increase the strength of immune system. In recent years, research on the use of nanoparticles in pharmaceuticals has been considered, most of which have been for ...
Seyed Shahaboddin Mousavi Motlagh+7 more
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Types of Conjugal Networks, Conjugal Conflict and Conjugal Quality [PDF]
This article considers how various configurations of network characteristics affect conjugal quality. To investigate this issue, we use data from a large survey on conjugal functioning, based on 910 married couples with co-resident children living in Switzerland. Using reports from both male and female partners, we first empirically define six types of
Widmer, Eric+2 more
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On-demand biomanufacturing of protective conjugate vaccines
In vitro conjugate vaccine expression technology enables rapid and portable biosynthesis of protective antibacterial vaccines. Conjugate vaccines are among the most effective methods for preventing bacterial infections.
Jessica C. Stark+12 more
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Most chemotherapeutic agents are nonspecific distribution and cause systemic toxicities. Polysaccharide-based conjugates are promising strategies to overcome these drawbacks.
Peng Dong+8 more
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Oligonucleotides with an amino linker at the 3′-end are useful for the preparation of conjugated oligonucleotides. However, chemically modified nucleosides, which are unstable under basic conditions, cannot be incorporated into oligonucleotides using the
Takashi Osawa, Qin Ren, Satoshi Obika
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