Results 91 to 100 of about 259,011 (271)

The revival of cancer vaccines — The eminent need to activate humoral immunity

open access: yesHuman Vaccines & Immunotherapeutics, 2017
In light of the increasing number of approved monoclonal antibodies for the treatment of cancer, it seems peculiar that the development of antibody inducing vaccines gets so little attention.
Elisabeth J. M. Huijbers   +1 more
doaj   +1 more source

Fixed Points of Generalized Conjugations [PDF]

open access: yesarXiv, 2008
Conjugation, or Legendre transformation, is a basic tool in convex analysis, rational mechanics, economics and optimization. It maps a function on a linear topological space into another one, defined in the dual of the linear space by coupling these space by meas of the duality product.
arxiv  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

On conjugates for set partitions and integer compositions [PDF]

open access: yesarXiv, 2005
There is a familiar conjugate for integer partitions: transpose the Ferrers diagram, and a conjugate for integer compositions: transpose a Ferrers-like diagram. Here we propose a conjugate for set partitions and show that it interchanges # singletons and # adjacencies. Its restriction to noncrossing partitions cropped up in a 1972 paper of Kreweras. We
arxiv  

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

EPITOPIC SPECIFICITY OF A SYNTHETIC DISACCHARIDE, RECURRING LINK OF CAPSULE POLYSACCHARIDE CHAIN OF SEROTYPE 3 STREPTOCCUS PNEUMONIAE

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Study epitopic specificity of synthetic disaccharide, recurring link of serotype 3 S. pneumoniae, conjugated with bovine serum albumin (BSA). Materials and methods.
E. A Kurbatova   +8 more
doaj  

Production and Application of Lysozyme-Gum Arabic Conjugate in Mayonnaise as a Natural Preservative and Emulsifier

open access: yesPolish Journal of Food and Nutrition Sciences, 2018
Nowadays demand for food products made by natural sources is rising so fast. In this work Lysozyme (Lyz) was conjugated with gum Arabic (GA) in order to be applied in mayonnaise, at which the presence of both preservative and emulsifier is essential ...
Hashemi Marjan M.   +6 more
doaj   +1 more source

Circularly squarefree words and unbordered conjugates: a new approach [PDF]

open access: yesarXiv, 2019
Using a new approach based on automatic sequences, logic, and a decision procedure, we reprove some old theorems about circularly squarefree words and unbordered conjugates in a new and simpler way. Furthermore, we prove three new results about unbordered conjugates: we complete the classification, due to Harju and Nowotka, of binary words with the ...
arxiv  

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