Results 101 to 110 of about 404,179 (310)

Boosting Photocatalytic Performance of ZnO Nanowires via Building Heterojunction with Conjugated 2,4,6-Triaminopyrimidine-g-C₃N₄

Molecules
Photocatalysis is one of the most effective ways to solve environmental problems by solving pollutants. This article designed and prepared a conjugated system of 2,4,6-triaminopyrimidine-g-C3N4 (TAP-CN) to modify ZnO NWs.
Jiahui Lou, Lihong Wang, Yaqiong Huang, Jun Xing, Xiaojie Yang   +4 more
doaj   +1 more source

Enhanced anti-hepatocarcinoma efficacy by GLUT1 targeting and cellular microenvironment-responsive PAMAM–camptothecin conjugate

Drug Delivery, 2018
The efficient targeting of drugs to tumor cell and subsequent rapid drug release remain primary challenges in the development of nanomedicines for cancer therapy.
Pengkai Ma, Yi Sun, Jianhua Chen, Hongpin Li, Hongyu Zhu, Xing Gao, Xinning Bi, Yujie Zhang   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Synthesis of Dextran–Phenoxodiol and Evaluation of Its Physical Stability and Biological Activity

Frontiers in Bioengineering and Biotechnology, 2019
Phenoxodiol, an isoflavene anti-tumor agent, was conjugated on the polysaccharide dextran using immobilized laccase as biocatalyst. The success of the enzymatic conjugation was determined by UV-vis spectrophotometry and its functionalization degree was ...
Eugene M. H. Yee, Giuseppe Cirillo, Miriam B. Brandl, Miriam B. Brandl, David StC Black, Orazio Vittorio, Orazio Vittorio, Naresh Kumar   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Multi-serotype pneumococcal nasopharyngeal carriage prevalence in vaccine naïve Nepalese children, assessed using molecular serotyping. [PDF]

, 2015
Invasive pneumococcal disease is one of the major causes of death in young children in resource poor countries. Nasopharyngeal carriage studies provide insight into the local prevalence of circulating pneumococcal serotypes.
Gurung, M, Kandasamy, Rama, Neelam Adhikari, David R Murdoch, Katherine A Gould, Murdoch, DR, Thapa, A, Adhikari, N, Hinds, Jason, Shrestha, S, Gould, Katherine A., Anushil Thapa, Kandasamy, R ; https://orcid.org/, Waldron, Denise E., Stephen Thorson, Rama Kandasamy, Waldron, DE, Gould, KA, Ndimah, S, Thorson, Stephen, Kelly, Dominic F., Shrijana Shrestha, Thorson, S, Dominic F Kelly, Meeru Gurung, Thapa, Anushil, Andrew J Pollard, Murdoch, David R., Ndimah, Susan, Shrestha, Shrijana, Denise E Waldron, Hinds, J, Pollard, Andrew J., Kandasamy, R, Adhikari, Neelam, Jason Hinds, Kelly, DF, Gurung, Meeru, Pollard, AJ, Pollard, Andrew, Susan Ndimah   +40 more
core   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Costs of vaccine delivery in the Gambia before and after, pentavalent and pneumococcal conjugate vaccine introductions.

, 2014
BACKGROUND: The Gambia introduced seven-valent pneumococcal conjugate vaccine (PCV) in August 2009 and switched to 13-valent PCV in April 2011. In April 2009 monovalent hepatitis B and combined Diphtheria-Tetanus-Pertussis and Haemophilus influenzae type
Lowe-Jallow, Y, Mackenzie, G, Atherly, D, Griffiths, UK, Boye, B, Usuf, E, Suraratdecha, C   +6 more
core   +1 more source

A Conjugate Gradient-Based BPTT-Like Optimal Control Algorithm With Vehicle Dynamics Control Application [PDF]

, 2010
The paper presents a gradient-based algorithm for optimal control of nonlinear multivariable systems with control and state vectors constraints. The algorithm has a backward-in-time recurrent structure similar to the backpropagation-through-time ...
Kolmanovsky, Ilya V., Novakovic, Branko, Joško Deur, Josip Kasac, Kasac, Josip, Francis Assadian, Branko Novakovic, Deur, Josko, Assadian, Francis, Kolmanovsky, Ilya, Ilya V. Kolmanovsky   +10 more
core   +1 more source

Synthesis and Biological Evaluation of Novel Water-Soluble Poly-(ethylene glycol)-10-hydroxycamptothecin Conjugates

Molecules, 2015
In order to improve the antitumor activity and water solubility of 10-hydroxycamptothecin (HCPT), a series of novel HCPT conjugates were designed and synthesized by conjugating polyethylene glycol (PEG) to the 10-hydroxyl group of HCPT via a valine ...
Na Guo, Du Jiang, Luyao Wang, Xing You, Yu-Ou Teng, Peng Yu   +5 more
doaj   +1 more source