Results 181 to 190 of about 259,011 (271)

Glutathione Contributes to Caloric Restriction-Triggered Shift in Taurine Homeostasis. [PDF]

Nutrients
Gregor A, Malleier M, Auñon-Lopez A, Auernigg-Haselmaier S, König J, Pignitter M, Duszka K.   +6 more
europepmc   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Effects of Conjugation with Basil Seed Gum on Physicochemical, Functional, Foaming, and Emulsifying Properties of Albumin, Whey Protein Isolate and Soy Protein Isolate. [PDF]

Foods
Hashemi H, Eskandari MH, Khalesi M, Golmakani MT, Niakousari M, Hosseini SMH.   +5 more
europepmc   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

Correction to: Immunogenicity and Safety of the Higher-Valent Pneumococcal Conjugate Vaccine vs the 13-Valent Pneumococcal Conjugate Vaccine in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials. [PDF]

Open Forum Infect Dis
europepmc   +1 more source

Opportunities and Challenges in Antibody-Drug Conjugates for Cancer Therapy: A New Era for Cancer Treatment. [PDF]

Cancers (Basel)
Buyukgolcigezli I, Tenekeci AK, Sahin IH.   +2 more
europepmc   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Inverse conjugate additions of acrylic amides and esters with F/Cl/O/N-nucleophiles and CF₃⁺ reagents. [PDF]

Sci Adv
Liu X, Kou Y, Wu H, Liu TX, Liu Q, Zhang Z, Zhang X, Zhang G.   +7 more
europepmc   +1 more source

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

FEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya, Ksenia V. Sergeeva, Boris S. Shenkman, Timur M. Mirzoev   +3 more
wiley   +1 more source

Economic Evaluation of Transitioning to the 20-Valent Pneumococcal Conjugate Vaccine in the Dutch Paediatric National Immunisation Programme. [PDF]

Infect Dis Ther
Çakar E, Ta A, Peters M, Vinand E, Waterval-Overbeek A, Ilic A, Perdrizet J.   +6 more
europepmc   +1 more source