Results 11 to 20 of about 914,037 (290)

Synergistic Effect of a HER2 Targeted Thorium-227 Conjugate in Combination with Olaparib in a BRCA2 Deficient Xenograft Model

open access: yesPharmaceuticals, 2019
Targeted thorium-227 conjugates (TTCs) represent a novel class of therapeutic radiopharmaceuticals for the treatment of cancer. TTCs consist of the alpha particle emitter thorium-227 complexed to a 3,2-hydroxypyridinone chelator conjugated to a tumor ...
Katrine Wickstroem   +11 more
doaj   +1 more source

Passive phase conjugate mirror based on self-induced oscillation in an optical ring cavity [PDF]

open access: yes, 1983
A passive phase conjugate mirror based on four-wave mixing in an optical ring cavity is described. Unlike previously demonstrated passive phase conjugate mirrors it generates only one of its pumping beams by nonlinear optical interactions, the other ...
Cronin-Golomb, Mark   +3 more
core   +1 more source

Instantaneous complex conjugate resolved spectral domain and swept-source OCT using 3x3 fiber couplers [PDF]

open access: yes, 2005
We report that the complex conjugate artifact in Fourier domain optical coherence tomography approaches (including spectral domain and swept source OCT) may be resolved by the use of novel interferometer designs based on 3x3 and higher order fiber ...
Choma, Michael A.   +3 more
core   +1 more source

Porphyrin as Diagnostic and Therapeutic Agent

open access: yesMolecules, 2019
The synthesis and application of porphyrins has seen a huge shift towards research in porphyrin bio-molecular based systems in the past decade. The preferential localization of porphyrins in tumors, as well as their ability to generate reactive singlet ...
Ncediwe Tsolekile   +2 more
doaj   +1 more source

Chloro-Substituted Naphthyridine Derivative and Its Conjugate with Thiazole Orange for Highly Selective Fluorescence Sensing of an Orphan Cytosine in the AP Site-Containing Duplexes

open access: yesApplied Sciences, 2020
Fluorescent probes with the binding selectivity to specific structures in DNAs or RNAs have gained much attention as useful tools for the study of nucleic acid functions.
Chun-xia Wang   +4 more
doaj   +1 more source

Conjugate DNAzymes [PDF]

open access: yesNucleic Acids Symposium Series, 2003
Conjugate DNAzymes were synthesized by solid phase fragment condensation and their biological properties were characterized. They have increased affinity to target RNA, enhanced stability against DNase 1 digestion and comparable or higher RNA cleaving activity compared with native and also phosphorothioate DNA zymes.
Takanori, Kubo   +4 more
openaire   +2 more sources

Types of Conjugal Networks, Conjugal Conflict and Conjugal Quality [PDF]

open access: yesEuropean Sociological Review, 2004
This article considers how various configurations of network characteristics affect conjugal quality. To investigate this issue, we use data from a large survey on conjugal functioning, based on 910 married couples with co-resident children living in Switzerland. Using reports from both male and female partners, we first empirically define six types of
Widmer, Eric   +2 more
openaire   +3 more sources

Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway [PDF]

open access: yes, 1993
Molecular conjugate vectors may be constructed that accomplish high efficiency gene transfer by the receptor-mediated endocytosis pathway. In order to mediate escape from lysosomal degradation, we have incorporated adenoviruses into the functional design
Curiel, David T.   +5 more
core   +2 more sources

Express ELISA for detection of mortalin

open access: yesBioTechniques, 2019
Mortalin is a widely studied stress chaperone that plays a significant role in diseases such as cancer, diabetes mellitus, liver cirrhosis, neurodegeneration and generalized aging. Based on these, the level of mortalin expression has been predicted to be
Sukant Garg   +4 more
doaj   +1 more source

Exact solution of a nonlinear model of four-wave mixing and phase conjugation [PDF]

open access: yes, 1982
An exact solution of a nonlinear model of holographic four-wave mixing is derived. An expression for the reflectivity of a phase-conjugate mirror with depleted pumps is presented.
Cronin-Golomb, Mark   +3 more
core   +1 more source

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