Results 291 to 300 of about 1,526,980 (375)

Antimicrobial and anti-cancer potential of turmeric synthesized AuNPs and Chitosan-AuNP nanocomposites against MDR pathogens and breast/colorectal carcinoma cells. [PDF]

AMB Express
Rejili MS, Haouala F, Abdulfattah AM, Alhomodi AF, Al-Zahrani M, Ellatif SA, Hafez EE, Abdelrazik ES.   +7 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Current Scientific Advances in Vaccines Against UTIs: Challenges and Prospects. [PDF]

Microorganisms
Wang B, Wang Y, Liu H, Yu M, Wang S, Liu L, Wang H, Zhang D, Tan H.   +8 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

The relationship between the Ewald sphere and exit wave explored using focal series electron micrographs. [PDF]

IUCrJ
Heymann JB.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A Multicatalytic Cascade for the Stereoselective Synthesis of 1,4-Chiral Nitro Alcohols. [PDF]

Org Lett
Ascaso-Alegre C, Linacero-Gracia Á, Ferreira P, Herrera RP, Mangas-Sánchez J.   +4 more
europepmc   +1 more source

Development and evaluation of siRNA-polymer conjugate for PIC-based siRNA delivery system

, 2013
宏泰 武元
openalex   +1 more source

Biomolecule-Photosensitizer Conjugates: A Strategy to Enhance Selectivity and Therapeutic Efficacy in Photodynamic Therapy. [PDF]

Pharmaceuticals (Basel)
Płaskonka DM, Barczyk D, Repetowski P, Warszyńska M, Dąbrowski JM.   +4 more
europepmc   +1 more source

Functional and structural analyses of UbcH5 mutants with enhanced binding to the E3 ubiquitin ligase CHIP. [PDF]

Biochem Biophys Res Commun
Manage MM, Nix JC, Page RC.
europepmc   +1 more source