Results 311 to 320 of about 1,526,980 (375)
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Enzyme-activatable polymer–drug conjugate augments tumour penetration and treatment efficacy
Nature Nanotechnology, 2019Jinqiang Wang, Zhuxian Zhou, Qingsong Yu
exaly +2 more sources
Novel antibody–antibiotic conjugate eliminates intracellular S. aureus
Nature, 2015Thomas H Pillow +2 more
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Small conjugate-based theranostic agents: an encouraging approach for cancer therapy
Chemical Society Reviews, 2015Rajesh Kumar, Kyoung Sunwoo, Seyoung Koo
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Journal of the American Chemical Society, 2014
Ping Huang, Yue Su, Yongfeng Zhou
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Ping Huang, Yue Su, Yongfeng Zhou
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ACS Nano, 2020
The dense fibrotic stroma in pancreatic ductal adenocarcinoma (PDA) resists drug diffusion into tumor and leads to unsatisfied prognosis. To address this problem, we demonstrate a dendrimer-camptothecin (CPT) conjugate that actively penetrates deep into ...
Guowei Wang +7 more
semanticscholar +1 more source
The dense fibrotic stroma in pancreatic ductal adenocarcinoma (PDA) resists drug diffusion into tumor and leads to unsatisfied prognosis. To address this problem, we demonstrate a dendrimer-camptothecin (CPT) conjugate that actively penetrates deep into ...
Guowei Wang +7 more
semanticscholar +1 more source
Domino Asymmetric Conjugate Addition–Conjugate Addition
Organic Letters, 2014Enantioenriched Al-, Mg-, and Zn-enolates undergo electrophilic trapping by nitroolefins and vinylsulfones to afford 1,4-diketones and 2-(bis(phenylsulfonyl)ethyl)ketones in good yield and excellent diastereoselectivity. A one-pot preparation of indenes and enantiopure syntheses of tetrahydrobenzofurans, tetrahydrobenzopyrroles, and azulenes are ...
Germain Nicolas +4 more
openaire +3 more sources
Annual Review of Microbiology, 1995
Conjugative transposons are important determinants of antibiotic resistance, especially in gram-positive bacteria. They are remarkably promiscuous and can conjugate between bacteria belonging to different species and genera. Transposon-promoted conjugation may be similar to F plasmid-promoted conjugation, as it appears that only one strand of the ...
J R, Scott, G G, Churchward
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Conjugative transposons are important determinants of antibiotic resistance, especially in gram-positive bacteria. They are remarkably promiscuous and can conjugate between bacteria belonging to different species and genera. Transposon-promoted conjugation may be similar to F plasmid-promoted conjugation, as it appears that only one strand of the ...
J R, Scott, G G, Churchward
openaire +2 more sources
Vaccine, 1985
Current interest in the development of sub-cellular vaccines and in cancer immunotherapy has rekindled interest in immunopotentiating agents. In addition, peptide sequences of protective antigens are being synthesized or genetically engineered and it is likely that these peptides will have a small relative molecular mass and be non-immunogenic by ...
openaire +2 more sources
Current interest in the development of sub-cellular vaccines and in cancer immunotherapy has rekindled interest in immunopotentiating agents. In addition, peptide sequences of protective antigens are being synthesized or genetically engineered and it is likely that these peptides will have a small relative molecular mass and be non-immunogenic by ...
openaire +2 more sources
Conjugate regenerative dividers
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2004We discuss a novel design of a self-starting regenerative divider that permits division by 3, 4, 5, 6 ... instead of the usual 2. This is accomplished by having the loop oscillate simultaneously at two harmonically related conjugate frequencies, e.g., at nu/4 and 3nu/4.
Amitava, Sen Gupta +2 more
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2005
Molecular conjugates are nanometer-sized entities consisting of synthetic materials (lipids, polycations, targeting agents, and so on) and nucleic acids. These composites are delivery vehicles that function to provide the transport of nucleic acids to sites of action. Recently, great progress has been made in the construction of these nonviral delivery
Jeremy, Heidel +2 more
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Molecular conjugates are nanometer-sized entities consisting of synthetic materials (lipids, polycations, targeting agents, and so on) and nucleic acids. These composites are delivery vehicles that function to provide the transport of nucleic acids to sites of action. Recently, great progress has been made in the construction of these nonviral delivery
Jeremy, Heidel +2 more
openaire +2 more sources