Results 31 to 40 of about 11,641,221 (293)

A new conjugate gradient method for acceleration of gradient descent algorithms

open access: yesMoroccan Journal of Pure and Applied Analysis, 2021
An accelerated of the steepest descent method for solving unconstrained optimization problems is presented. which propose a fundamentally different conjugate gradient method, in which the well-known parameter βk is computed by an new formula.
Rahali Noureddine   +2 more
doaj   +1 more source

A New Modified Conjugate Gradient for Nonlinear Minimization Problems

open access: yesScience Journal of University of Zakho, 2022
The conjugate gradient is a highly effective technique to solve the unconstrained nonlinear minimization problems and it is one of the most well-known methods. It has a lot of applications.
Hussein Ageel Khatab, Salah G. Sharef
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Two Versions of the Spectral Nonlinear Conjugate Gradient Method

open access: yesAl-Mustansiriyah Journal of Science, 2018
The nonlinear conjugate gradient method is widely used to solve unconstrained optimization problems. In this paper the development of different versions of nonlinear conjugate gradient methods with global convergence properties proved.
Basim A. Hassan, Haneen A. Alashoor
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Conjugate Gradient Method with Global Convergence for Large-Scale Unconstrained Optimization Problems

open access: yesJournal of Applied Mathematics, 2013
The conjugate gradient (CG) method has played a special role in solving large-scale nonlinear optimization problems due to the simplicity of their very low memory requirements.
Shengwei Yao, Xiwen Lu, Zengxin Wei
doaj   +1 more source

Two efficient modifications of AZPRP conjugate gradient method with sufficient descent property

open access: yesJournal of Inequalities and Applications, 2022
The conjugate gradient method can be applied in many fields, such as neural networks, image restoration, machine learning, deep learning, and many others.
Zabidin Salleh   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Algorithm for Scaling Variables in Minimization Methods

open access: yesAlgorithms
Eliminating poor scaling of variables of minimized functions is a pressing issue in solving high-dimensional minimization problems where it is impossible to use methods that change the metric of the space with full-scale metric matrices.
Elena Tovbis   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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