Results 51 to 60 of about 178,281 (234)

Chebyshev semi-iteration in Preconditioning [PDF]

open access: yes, 2008
It is widely believed that Krylov subspace iterative methods are better than Chebyshev semi-iterative methods. When the solution of a linear system with a symmetric and positive definite coefficient matrix is required then the Conjugate Gradient method ...
Rees, Tyrone, Wathen, A. J.
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Nonlinear Conjugate Gradient Methods with Wolfe Type Line Search

open access: yesAbstract and Applied Analysis, 2013
Nonlinear conjugate gradient method is one of the useful methods for unconstrained optimization problems. In this paper, we consider three kinds of nonlinear conjugate gradient methods with Wolfe type line search for unstrained optimization problems ...
Yuan-Yuan Chen, Shou-Qiang Du
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

A Mixed Spectral CD-DY Conjugate Gradient Method

open access: yesJournal of Applied Mathematics, 2012
A mixed spectral CD-DY conjugate descent method for solving unconstrained optimization problems is proposed, which combines the advantages of the spectral conjugate gradient method, the CD method, and the DY method.
Liu Jinkui, Du Xianglin, Wang Kairong
doaj   +1 more source

Chronological Inversion Method for the Dirac Matrix in Hybrid Monte Carlo

open access: yes, 1996
In Hybrid Monte Carlo simulations for full QCD, the gauge fields evolve smoothly as a function of Molecular Dynamics time. Here we investigate improved methods of estimating the trial or starting solutions for the Dirac matrix inversion as superpositions
A.R. Levi   +27 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Nonlinear conjugate gradient methods in micromagnetics

open access: yesAIP Advances, 2017
Conjugate gradient methods for energy minimization in micromagnetics are compared. The comparison of analytic results with numerical simulation shows that standard conjugate gradient method may fail to produce correct results. A method that restricts the
J. Fischbacher   +11 more
doaj   +1 more source

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