Results 61 to 70 of about 819,121 (316)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Reducing Impulse Noise in Images Using an Improved Formula Conjugate Gradient Method
Zanco Journal of Pure and Applied SciencesThe conjugate formula's significance is frequently emphasised by conjugate gradient approaches. In this paper, a novel conjugate coefficient for the conjugate gradient technique is introduced using a quadratic model and conjugacy condition.
Basim A. Hassan, Yousif Ali Mohammed
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Heliyon, 2020 Combining the projection method of Solodov and Svaiter with the Liu-Storey and Fletcher Reeves conjugate gradient algorithm of Djordjević for unconstrained minimization problems, a hybrid conjugate gradient algorithm is proposed and extended to solve ...
Abdulkarim Hassan Ibrahim +4 more
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A new conjugate gradient method for acceleration of gradient descent algorithms
Moroccan Journal of Pure and Applied Analysis, 2021 An accelerated of the steepest descent method for solving unconstrained optimization problems is presented. which propose a fundamentally different conjugate gradient method, in which the well-known parameter βk is computed by an new formula.
Rahali Noureddine +2 more
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Conjugate Gradient Methods for Toeplitz Systems [PDF]
SIAM Review, 1996 The use of preconditioned conjugate gradient methods to solve linear systems of equations with Toeplitz matrices is discussed. Using this iterative method, the complexity is reduced from \(O(n\log^2n)\) operations for fast direct Toeplitz solvers to \(O(n \log n)\).
Chan, Raymond H., Ng, Michael K.
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Enhancing Conjugate Gradient Method Through a Novel Investigation Parameter For Unconstrained Minimization [PDF]
مجلة التربية والعلمConjugate gradient algorithms come in a wide range of flavors. The conjugate gradient technique primarily concentrates on the spectral parameter. It follows the standard method proposed by Hastens and Stiefel, In this study, we have devised an innovative
Abd Hassan, Hamsa Saeed
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Stability Analysis Of Continuous Conjugate Gradient Method [PDF]
, 2008 Kaedah Conjugate Gradient adalah sangat berguna untuk: menyelesaikan masalah tiada kekangan paling optimum yang berskala besar. Walaubagaimanapun, carlan garis (line search) dalam Kaedah Conjugate Gradient kadang-kadang sukar didapati dan pengiraannya
Harun, Nurzalina
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source