Results 61 to 70 of about 178,281 (234)

A new conjugate gradient method with a restart direction and its application in image restoration

AIMS Mathematics, 2023
We established a new conjugate gradient method with an efficient restart direction for solving large scale unconstrained optimization problems. The modified method was proposed under the Polak-Ribière-Polyak conjugate gradient method.
Yixin Li, Chunguang Li , Wei Yang, Wensheng Zhang   +3 more
doaj   +1 more source

Penyelesaian Persamaan Poisson 2D dengan Menggunakan Metode Gauss-Seidel dan Conjugate Gradien [PDF]

, 2017
In this paper we focus on solution of 2D Poisson equation numerically. 2D Poisson equation is a partial differential equation of second order elliptical type. This equation is a particular form or non-homogeneous form of the Laplace equation.
Mahmudah, D. E. (Dewi), Naf\u27an, M. Z. (Muhammad)   +1 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Numerical Evidence of Luttinger and Fermi Liquid Behaviour in the 2D Hubbard Model

, 1993
The two dimensional Hubbard model with a single spin-up electron interacting with a finite density of spin-down electrons is studied using the quantum Monte Carlotechnique, a new conjugate gradient method for the evaluation of the Edwards wavefunction ...
A. Parola, C. C. Tsuei, D. M. Edwards, D. M. Frenkel, E. H. Lieb, H. Castella, H. Schulz, I. uStich, J. E. Hirsch, J. R. Engelbrecht, J. R. Engelbrecht, M. Fabrizio, P. C. Puttnaik, P. W. Anderson, P. W. Anderson, P. W. Anderson, S. R. White, S. Sorella, Sandro Sorella, W. von der Linden   +19 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A Novel hybridization of CG-techniques for Solving Unconstrained Optimization Problems

Wasit Journal for Pure Sciences
Conjugate gradient methods are an extremely helpful way for handling large scale non-linear optimization issues. In this paper, based on the three famous Dai-yuan (DY), Liu–Storey (LS)and Conjugate-Descent (CD) conjugate gradient methods, a new hybrid ...
Hawraz Jabbar
doaj   +1 more source

A New Smoothing Conjugate Gradient Method for Solving Nonlinear Nonsmooth Complementarity Problems

Algorithms, 2015
In this paper, by using the smoothing Fischer-Burmeister function, we present a new smoothing conjugate gradient method for solving the nonlinear nonsmooth complementarity problems.
Ajie Chu, Shouqiang Du, Yixiao Su
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Development of a Spectral Conjugate Gradient Method for Solving Optimization Problems

Al-Rafidain Journal of Computer Sciences and Mathematics
Conjugate gradient methods have been favored to use for their efficiency in solving large-scale unconstrained optimization problems, primarily because of their low memory requirements and exclusive to use the first-order derivative information.
Kamal Jameel Murad, Salah Gazi Shareef
doaj   +1 more source

Dai-Kou type conjugate gradient methods with a line search only using gradient

Journal of Inequalities and Applications, 2017
In this paper, the Dai-Kou type conjugate gradient methods are developed to solve the optimality condition of an unconstrained optimization, they only utilize gradient information and have broader application scope.
Yuanyuan Huang, Changhe Liu
doaj   +1 more source