Results 61 to 70 of about 109,308 (284)

Multivariate Bayesian Global–Local Shrinkage Methods for Regularisation in the High-Dimensional Linear Model

Mathematics
This paper considers Bayesian regularisation using global–local shrinkage priors in the multivariate general linear model when there are many more explanatory variables than observations.
Valentina Mameli, Debora Slanzi, Jim E. Griffin, Philip J. Brown   +3 more
doaj   +1 more source

A Two-Stage Maximum Entropy Prior of Location Parameter with a Stochastic Multivariate Interval Constraint and Its Properties

Entropy, 2016
This paper proposes a two-stage maximum entropy prior to elicit uncertainty regarding a multivariate interval constraint of the location parameter of a scale mixture of normal model.
Hea-Jung Kim
doaj   +1 more source

Photoinduced membrane damage of E. coli and S. aureus by the photosensitizer-antimicrobial peptide conjugate eosin-(KLAKLAK)2. [PDF]

PLoS ONE, 2014
BACKGROUND/OBJECTIVES: Upon irradiation with visible light, the photosensitizer-peptide conjugate eosin-(KLAKLAK)2 kills a broad spectrum of bacteria without damaging human cells. Eosin-(KLAKLAK)2 therefore represents an interesting lead compound for the
Gregory A Johnson, E Ann Ellis, Hansoo Kim, Nandhini Muthukrishnan, Thomas Snavely, Jean-Philippe Pellois   +5 more
doaj   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

Safety and immunogenicity of 15-valent pneumococcal conjugate vaccine compared to 13-valent pneumococcal conjugate vaccine in adults ≥65 years of age previously vaccinated with 23-valent pneumococcal polysaccharide vaccine

Human Vaccines & Immunotherapeutics, 2019
Background: Pneumococcal disease remains a public health priority in adults. Previous studies have suggested that administration of pneumococcal polysaccharide vaccine or pneumococcal conjugate vaccine within three years following receipt of PPV23 was ...
James T. Peterson, Helen L. Stacey, John E. MacNair, Jianing Li, Jonathan S. Hartzel, Tina M. Sterling, Patrice Benner, Gretchen M. Tamms, Luwy K. Musey   +8 more
doaj   +1 more source

The impact of meningococcal conjugate vaccine (MenACWY-TT) on meningococcal carriage in Hajj Pilgrims returning to Turkey

Human Vaccines & Immunotherapeutics, 2020
Meningococcal conjugate vaccine was administered for the first time to pilgrims in 2018 in Turkey prior to their departure to the Hajj. This study aimed to determine the effect of vaccination on the prevalence of Neisseria meningitidis carriage among the
Hasan Tezer, Belgin Gülhan, Ayşe Simge Gişi, Selin Nar Ötgün, Saliha Kanık-Yüksek, Aslınur Özkaya-Parlakay, Selçuk Kılıç, Nuriye Ünal Şahin, Asiye Çiğdem Şimşek, Ateş Kara   +9 more
doaj   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

E-Bayesian Estimation for the Exponential Model Based on Record Statistics

Journal of Statistical Theory and Applications (JSTA), 2019
This paper is concerned with using the E-Bayesian method for computing estimates for the parameter and reliability function of the Exponential distribution based on a set of upper record statistics values.
Hassan M. Okasha
doaj   +1 more source

A conjugate prior for the Dirichlet distribution

, 2018
This note investigates a conjugate class for the Dirichlet distribution class in the exponential family.
openaire   +2 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source