Results 121 to 130 of about 45,310 (260)

Pneumococcal Vaccines: The Impact of Conjugate Vaccine:Pneumococcal Vaccines: The Impact of Conjugate Vaccine [PDF]

Clinical Infectious Diseases, 2008
openaire   +1 more source

From Crisis to Control: A Study of Typhoid Conjugate Vaccine Efficacy in Harare, Zimbabwe (2017-2024). [PDF]

Open Forum Infect Dis
Bvochora T, Manyara J, Thilliez G, Vere M, Mukeredzi I, Nhamo D, Chitiyo F, Muzondo A, Juru A, Chonzi P, Phiri I, Smith AM, Chaibva BV, Mapingure M, Fuller W, Shrestha P, Nair P, Kingsley RA, Laxminarayan R, Musuka G, Mashe T.   +20 more
europepmc   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Examining epidemiological models and economic analyses of typhoid conjugate vaccine: A scoping review. [PDF]

PLOS Glob Public Health
Mandaliya P, Orangi S, Kazungu J, Waithaka D, Kairu A, Bationo A, Masiye F, Onwujekwe O, Barasa E.   +8 more
europepmc   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Correction: Impact of the COVID-19 pandemic and typhoid conjugate vaccine introduction on typhoid fever in Nepal. [PDF]

PLoS Negl Trop Dis
Tamrakar D, Naga SR, Jung E, Shrestha B, Bista Roka P, Pokharel R, Shahi SB, Bajracharya AT, Mahadup SK, Katuwal N, Doyle K, Seidman JC, Carter AS, Luby SP, Bogoch II, Aiemjoy K, Garrett DO, Shrestha R, Andrews JR.   +18 more
europepmc   +1 more source

PROTAC‐Engineered Protein/DNA Nanoantigen is a Potent Booster for Dendritic Cell Vaccines in Cancer Immunotherapy

Advanced Science, EarlyView.
A PROTAC‐functionalized protein/DNA‐integrated nanoantigen platform is developed to enhance dendritic cell vaccine potency. By combining a VHL‐recruiting peptide‐modified antigen with a sustained expression plasmid within CaCO3 nanoparticles, this system amplifies cross‐presentation, promotes DC maturation, and elicits robust Th1 and CTL responses ...
Peng Liu, Qiang Chen, Zhe Zhou, Yuekang Xu, Jinyao Li   +4 more
wiley   +1 more source

Development and validation of immunological assays for preclinical evaluation of a novel bivalent typhoid conjugate vaccine. [PDF]

Hum Vaccin Immunother
Gavade V, Kamat C, Avalaskar N, Haridasyam V, Sargar S, Chavan A, Jadhav V, Kadam S, Borude B, Sarma AD, Mallya A, Dhere RM.   +11 more
europepmc   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

Advanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao, Yuting Liu, Xiao Huang, Liwen Zhao, Chunli Li, Yongwei Huang   +5 more
wiley   +1 more source

Adult Pneumococcal Vaccination in Latin America: The Next Step Beyond Pediatric Pneumococcal Conjugate Vaccine. [PDF]

Cureus
Zavaleta-Monestel E, Arguedas-Chacón S, Mora-Jiménez J, Díaz-Madriz JP, Herrera-Jiménez LG.   +4 more
europepmc   +1 more source