Results 21 to 30 of about 1,038,868 (220)

Mutant Native Outer Membrane Vesicles Combined with a Serogroup A Polysaccharide Conjugate Vaccine for Prevention of Meningococcal Epidemics in Africa. [PDF]

PLoS ONE, 2013
The meningococcal serogroup A (MenA) polysaccharide conjugate vaccine used in Sub-Saharan Africa does not prevent disease caused by MenW or MenX strains, which also cause epidemics in the region.
Rolando Pajon, Andrew M Fergus, Dan M Granoff   +2 more
doaj   +1 more source

Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China

Human Vaccines & Immunotherapeutics, 2022
Given increased global concern about vaccine hesitancy, this study estimates coverage of mandatory vs non-mandatory vaccines in children, and assesses whether vaccine hesitancy among young parents relates to their childʻs eventual vaccination status in ...
Mengdi Ji, Zhuoying Huang, Jia Ren, Abram L. Wagner   +3 more
doaj   +1 more source

Conjugation of HIV-1 envelope to hepatitis B surface antigen alters vaccine responses in rhesus macaques

npj Vaccines, 2023
An effective HIV-1 vaccine remains a critical unmet need for ending the AIDS epidemic. Vaccine trials conducted to date have suggested the need to increase the durability and functionality of vaccine-elicited antibodies to improve efficacy.
Danielle Nettere, Shakthi Unnithan, Nicole Rodgers, Junsuke Nohara, Paul Cray, Madison Berry, Caroline Jones, Lawrence Armand, Shuk Hang Li, Stella J. Berendam, Genevieve G. Fouda, Derek W. Cain, Taylor N. Spence, Joshua A. Granek, Clemontina A. Davenport, Robert J. Edwards, Kevin Wiehe, Koen K. A. Van Rompay, M. Anthony Moody, Sallie R. Permar, Justin Pollara   +20 more
doaj   +1 more source

Vaccines against Meningococcal Diseases

Microorganisms, 2020
Neisseria meningitidis is the main cause of meningitis and sepsis, potentially life-threatening conditions. Thanks to advancements in vaccine development, vaccines are now available for five out of six meningococcal disease-causing serogroups (A, B, C, W,
Mariagrazia Pizza, Rafik Bekkat-Berkani, Rino Rappuoli   +2 more
doaj   +1 more source

Co-evolution of Vaccination Behavior and Perceived Vaccination Risk can lead to a Stag-Hunt like Game [PDF]

, 2022
Voluntary vaccination is effective to prevent infectious diseases from spreading. Both vaccination behavior and cognition of the vaccination risk play important roles in individual vaccination decision making. However, it is not clear how the co-evolution of the two shapes the population-wide vaccination behavior.
arxiv   +1 more source

Safety, Tolerability, and Immunogenicity of a 20-Valent Pneumococcal Conjugate Vaccine (PCV20) in Adults 60 to 64 Years of Age

Clinical Infectious Diseases, 2020
Background Pneumococcal conjugate vaccines (PCVs) have significantly decreased pneumococcal disease worldwide; however, expanding serotype coverage may further reduce disease burden.
D. Hurley, C. Griffin, Mariano M Young, D. Scott, M. Pride, Ingrid L Scully, John Ginis, Joseph M. Severs, K. Jansen, W. Gruber, W. Watson   +10 more
semanticscholar   +1 more source

High residual carriage of vaccine-serotype Streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in Malawi

Nature Communications, 2020
There are concerns that pneumococcal conjugate vaccines (PCVs) in sub-Saharan Africa sub-optimally interrupt Streptococcus pneumoniae vaccine-serotype (VT) carriage and transmission.
T. Swarthout, C. Fronterrè, J. Lourenço, U. Obolski, A. Gori, N. Bar-Zeev, D. Everett, A. Kamng’ona, T. Mwalukomo, A. A. Mataya, C. Mwansambo, Marjory Banda, Sunetra Gupta, P. Diggle, N. French, R. Heyderman   +15 more
semanticscholar   +1 more source

Accurate Measures of Vaccination and Concerns of Vaccine Holdouts from Web Search Logs [PDF]

, 2023
To design effective vaccine policies, policymakers need detailed data about who has been vaccinated, who is holding out, and why. However, existing data in the US are insufficient: reported vaccination rates are often delayed or missing, and surveys of vaccine hesitancy are limited by high-level questions and self-report biases. Here, we show how large-
arxiv   +1 more source

RNA gene profile variation in peripheral blood mononuclear cells from rhesus macaques immunized with Hib conjugate vaccine, Hib capsular polysaccharide and TT carrier protein

BMC Immunology, 2018
Background The Haemophilus influenzae type b (Hib) conjugate vaccine has been widely used in children to prevent invasive Hib disease because of its strong immunogenicity and antibody response induction relative to the capsular polysaccharide (CPS ...
Jing Tang, Ying Zhang, Xiaolong Zhang, Yun Liao, Yongrong Wang, Shengjie Ouyang, Yanchun Che, Miao Xu, Jing Pu, Qi Shen, Zhanlong He, Qiang Ye, Qihan Li   +12 more
doaj   +1 more source

Long Term Impact of Conjugate Vaccines on Haemophilus influenzae Meningitis: Narrative Review

Microorganisms, 2021
H. influenzae serotype b (Hib) used to be the commonest cause of bacterial meningitis in young children. The widespread use of Hib conjugate vaccine has profoundly altered the epidemiology of H. influenzae meningitis.
Mary Paulina Elizabeth Slack
doaj   +1 more source