Results 291 to 300 of about 1,208,196 (340)
Some of the next articles are maybe not open access.
siRNA Conjugate Delivery Systems
Bioconjugate Chemistry, 2008Small interfering RNA (siRNA) has been chemically conjugated to a variety of bioactive molecules, lipids, polymers, peptides, and inorganic nanostructured materials to enhance their pharmacokinetic behavior, cellular uptake, target specificity, and safety. To efficiently deliver siRNAs to the target cells and tissues, many different siRNA bioconjugates
Jeong, JH Jeong, Ji Hoon +3 more
openaire +3 more sources
The Ubiquitin-Conjugation System
Annual Review of Genetics, 1992The ubiquitin/proteasome system is believed to be the major nonlysosomal proteolytic system of eukaryotic cells. It is present in the cytosol and the nucleus but apparently absent from the lumen of membrane-enclosed organelles, i. e., the endoplasmic reticulum, the Golgi and vesicular system, mitochondria, chloroplasts, and peroxisomes (for reviews see
openaire +3 more sources
The Journal of Biochemistry, 2005
ISG15 is a ubiquitin-like protein that is upregulated on treatment with interferon. ISG15 is considered to be covalently conjugated to cellular proteins through a sequential reaction similar to that of the ubiquitin conjugation system consisting of E1/E2/E3 enzymes: UBE1L and UbcH8 have been reported to function as E1 and E2 enzymes, respectively, for ...
Tomoharu Takeuchi +4 more
openaire +3 more sources
ISG15 is a ubiquitin-like protein that is upregulated on treatment with interferon. ISG15 is considered to be covalently conjugated to cellular proteins through a sequential reaction similar to that of the ubiquitin conjugation system consisting of E1/E2/E3 enzymes: UBE1L and UbcH8 have been reported to function as E1 and E2 enzymes, respectively, for ...
Tomoharu Takeuchi +4 more
openaire +3 more sources
Effective conjugation length of π-conjugated systems
Chemical Physics Letters, 2004Abstract The optical absorption of ordered and disordered π-conjugated molecules is described on the same microscopic footing. This gives a concise picture of the length dependence of the optical absorption of π-conjugated systems.
openaire +2 more sources
Conjugation and the periodic system of the elements
Russian Chemical Reviews, 1991The knowledge of the characteristics and mechanisms of the interaction of the active centres of complex molecules is of primary importance for the development of theoretical and applied organic chemistry, promotes a more productive utilisation of the enormous amount of experimental data available, facilitates predictions and the search for new routes ...
Konstantin Ya Burshtein, P. P. Shorygin
openaire +2 more sources
PMO Treatment of Conjugated Systems
1975In order to apply the formal scheme developed in the previous chapter, we have to have some way of estimating the various quantities that appear in the perturbation expressions. These fall into two categories, the integral terms and the AO coefficients.
Michael J. S. Dewar, Ralph C. Dougherty
openaire +2 more sources
?, ? Conjugation in organometallic systems
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1979In concluding it should be noted that the data presented in the present work support the results of earlier chemical studies [1, 2, 7], insofar as they show that conjugation of the C-Hg bond with C=O and C=C bonds is realized in the mercury derivatives of the acyclic and monocyclic ketones and aldehydes, and their ally 1-type analogs.
openaire +2 more sources
Colour and topology of conjugated systems
Journal of Molecular Structure, 1990Abstract Colour of polymethine dyes is theoretically characterized by topological indices of their end-groups: the effective length and the electron donor ability. These parameters can be calculated and interpreted through various approaches, involving the formalism of graph theory. The account of the electronic interaction is discussed.
Aleksey D. Kachkovsky +2 more
openaire +2 more sources
Isomerization of conjugated and cumulated systems
Recueil des Travaux Chimiques des Pays-Bas, 1967AbstractVarious compounds with the system and have been converted into conjugated trienes by means of potassium tert‐butoxide in dimethyl sulfoxide (DMSO).
J. H. Van Boom +5 more
openaire +2 more sources
ChemInform Abstract: Organometallic π‐Conjugated Systems
ChemInform, 1995AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
openaire +3 more sources