Results 51 to 60 of about 1,208,196 (340)

LC3 conjugation system in mammalian autophagy

The International Journal of Biochemistry & Cell Biology, 2004
Autophagy is the bulk degradation of proteins and organelles, a process essential for cellular maintenance, cell viability, differentiation and development in mammals. Autophagy has significant associations with neurodegenerative diseases, cardiomyopathies, cancer, programmed cell death, and bacterial and viral infections.
Isei Tanida, Takashi Ueno, Eiki Kominami
openaire   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Hydroxyl Group as the ‘Bridge’ to Enhance the Single-Molecule Conductance by Hyperconjugation

Molecules
For designing single-molecule devices that have both conjugation systems and structural flexibility, a hyperconjugated molecule with a σ–π bond interaction is considered an ideal candidate. In the investigation of conductance at the single-molecule level,
Xin Lv, Chang Li, Meng-Meng Guo, Wenjing Hong, Li-Chuan Chen, Qian-Chong Zhang, Zhong-Ning Chen   +6 more
doaj   +1 more source

Highly Conducting pi-Conjugated Molecular Junctions Covalently Bonded to Gold Electrodes

, 2011
We measure electronic conductance through single conjugated molecules bonded to Au metal electrodes with direct Au-C covalent bonds using the scanning tunneling microscope based break-junction technique.
Beebe J. M., Brandbyge M., Calzolari A., Chen F., Cheng Z. L., Cohen T., Darancet P., Evers F., Haiss W., Hybertsen M. S., Héctor Vázquez, Joachim C., Jonathan R. Widawsky, Ke S. H., Kiguchi M., Kiguchi M., Kosov D. S., Latha Venkataraman, Li C., Li X. L., Ma G. H., Mark S. Hybertsen, Martin C. A., Mishchenko A., Neaton J. B., Nitzan A., Park Y. S., Park Y. S., Paulsson M., Perdew J. P., Quek S. Y., Quek S. Y., Reed M. A., Ronald Breslow, Sai N., Schneebeli S. T., Severin T. Schneebeli, Smit R. H. M., Soler J. M., Still W. C., Still W. C., Strange M., Thygesen K. S., Thygesen K. S., Toher C., Venkataraman L., Venkataraman L., von Wrochem F., Wenbo Chen, Xu B. Q.   +49 more
core   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Study of immunogenic properties of transmissible gastroenteritis virus antigen conjugated to gold nanoparticles

Journal of Biomedical Photonics & Engineering, 2016
There was performed the study of immunogenic properties of the transmissible gastroenteritis virus antigen conjugated to gold nanoparticles. In comparative immunobiological studies there was found that immunization of guinea pigs driven by the colloidal ...
Pavel V. Mezhenny, Sergej A. Staroverov, Aleksandr S. Fomin, Aleksej A. Volkov, Ivan Y. Domnitsky, Sergey V. Kozlov, Vladislav N. Laskavy, Lev A. Dykman   +7 more
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Effect of π-conjugated molecules on electronics properties of benzene-diamine derivatives

Iraqi Journal of Physics, 2021
The present work shows a theoretical results that have been used the functional Hybrid of three parameters Lee-Yang-Parr (B3LYP) of the quantum mechanical approach for density functional theory with (Spanish Initiative for Electronic Simulations with ...
Mohsin Al-Khaykanee, Ali Al-Jawdahb
doaj   +1 more source

Algebra of differential operators associated with Young diagrams

, 2010
We establish a correspondence between Young diagrams and differential operators of infinitely many variables. These operators form a commutative associative algebra isomorphic to the algebra of the conjugated classes of finite permutations of the set of ...
A. Mironov, A. Morozov, Alexeevski, Alexeevski, Alexeevski, Arnold, Bouchard, Cordes, Dijkgraaf, Goulden, Gross, Hurwitz, Ivanov, Kazarian, Kazarian, Kharchev, Kharchev, Kostov, Macdonald, Mironov, Mironov, Miwa, Morozov, Morozov, Natanzon, Okounkov, Okounkov, Okounkov, S. Natanzon, Zhelobenko   +29 more
core   +1 more source