Results 61 to 70 of about 1,208,196 (340)

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Significantly Enhanced Molecular Stacking in Ternary Bulk Heterojunctions Enabled by an Appropriate Side Group on Donor Polymer

open access: yesAdvanced Science, 2020
Ternary strategy is a promising approach to broaden the photoresponse of polymer solar cells (PSCs) by adopting combinatory photoactive blends. However, it could lead to a more complicated situation in manipulating the bulk morphology. Achieving an ideal
Huanxiang Jiang   +8 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Electron correlation effects and two-photon absorption in diamond shaped graphene quantum dots

open access: yes, 2018
In quasi-1D $\pi$-conjugated polymers such as \emph{trans}-polyacetylene and polyenes, electron correlation effects determine the "reversed" excited state ordering in which the lowest two-photon $2A_{g}$ state lies below the lowest one-photon $1B_{u ...
Basak, Tista   +2 more
core   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Second-generation aptamer-conjugated PSMA-targeted delivery system for prostate cancer therapy

open access: yesInternational Journal of Nanomedicine, 2011
Xin Wu1,*, Baoyue Ding1,2,*, Jing Gao3,*, Huanyun Wang4, Wei Fan1, Xiang Wang1,5, Wei Zhang1, Xiaoyu Wang1, Lihua Ye1, Min Zhang1, Xueying Ding3, Jiyong Liu1, Quangang Zhu1, Shen Gao11Department of Pharmaceutics, Changhai Hospital, Second Military ...
Zhu Q   +13 more
doaj  

Vibration-enhanced quantum transport

open access: yes, 2010
In this paper, we study the role of collective vibrational motion in the phenomenon of electronic energy transfer (EET) along a chain of coupled electronic dipoles with varying excitation frequencies.
Asadian A   +12 more
core   +1 more source

Review of Conjugated Porphyrin Systems

open access: yes, 2020
Porphyrin macromolecules play critical roles in many natural processes. Studies are going on to mimic their role in natural systems and use them in various applications in artificial systems. When a porphyrin moiety is conjugated with carbon nanoallotropes, viz., carbon nanomaterials, carbon nanotubes, carbon nanospheres, etc., the hybrid molecules ...
optoelectronics material   +2 more
openaire   +2 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

3-Acetoxy-2-naphthoic acid

open access: yesActa Crystallographica Section E, 2010
In the title compound, C13H10O4, an analog of acetylsalicylic acid, the naphthalene unit is twisted slightly due to ortho disubstitution [dihedral angle between conjugated rings system in the naphthalene unit = 2.0 (2)°].
Bruno S. Souza   +4 more
doaj   +1 more source

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