Results 61 to 70 of about 1,234,343 (276)
Perinatal development of conjugative enzyme systems. [PDF]
Environmental Health Perspectives, 1976 The problems and priorities involved in studying the role of conjugagive enzymes in developmental pharmacology are discussed and evaluated. The relative rates of UDP glucuronyltransferase and beta-glucuronidase were studied during perinatal development in hepatic and extrahepatic tissues to determine the net balance of glucuronidation or ...
openaire +3 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Symmetry Induced 4-Wave Capillary Wave Turbulence
, 2009 We report theoretical and experimental results on 4-wave capillary wave turbulence. A system consisting of two inmiscible and incompressible fluids of the same density can be written in a Hamiltonian way for the conjugated pair $(\eta,\Psi)$.
Claudio Falcón +7 more
core +1 more source
Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases
FEBS Letters, EarlyView.Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic +2 more
wiley +1 more source
Nanomaterials, 2023 Multidrug resistance (MDR) is the main challenge in cancer treatment. In this sense, we designed transferrin (Tf)-conjugated PLGA nanoparticles (NPs) containing an organoselenium compound as an alternative to enhance the efficacy of cancer therapy and ...
Letícia Bueno Macedo +8 more
doaj +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Pharmaceutics, 2023 The objective of this study was to construct amodiaquine-loaded, folic acid-conjugated polymeric nanoparticles (FA-AQ NPs) to treat cancer that could be scaled to commercial production.
Vineela Parvathaneni +2 more
doaj +1 more source
Review of Conjugated Porphyrin Systems
, 2020 Porphyrin macromolecules play critical roles in many natural processes. Studies are going on to mimic their role in natural systems and use them in various applications in artificial systems. When a porphyrin moiety is conjugated with carbon nanoallotropes, viz., carbon nanomaterials, carbon nanotubes, carbon nanospheres, etc., the hybrid molecules ...
optoelectronics material +2 more
openaire +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Second-generation aptamer-conjugated PSMA-targeted delivery system for prostate cancer therapy
International Journal of Nanomedicine, 2011 Xin Wu1,*, Baoyue Ding1,2,*, Jing Gao3,*, Huanyun Wang4, Wei Fan1, Xiang Wang1,5, Wei Zhang1, Xiaoyu Wang1, Lihua Ye1, Min Zhang1, Xueying Ding3, Jiyong Liu1, Quangang Zhu1, Shen Gao11Department of Pharmaceutics, Changhai Hospital, Second Military ...
Zhu Q +13 more
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