Results 11 to 20 of about 164,481 (302)
Oligonucleotide-conjugated beads for transdominant genetic experiments [PDF]
Nucleic Acids Research, 2000 Transdominant genetics using expression libraries can identify proteins and peptides that affect cell division. In conjunction with these libraries, oligo-nucleotide-conjugated beads and flow cytometry were used to test a strategy that potentially expands the range of such genetic studies.
M J, Feldhaus +4 more
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Multiple Layered Control of the Conjugation Process of the Bacillus subtilis Plasmid pLS20
Frontiers in Molecular Biosciences, 2021 Bacterial conjugation is the main horizontal gene transfer route responsible for the spread of antibiotic resistance, virulence and toxin genes.
Wilfried J. J. Meijer +6 more
doaj +1 more source
Genetic organization of the bacterial conjugative transposon Tn916 [PDF]
Journal of Bacteriology, 1988 Tn916, which encodes resistance to tetracycline, is a 16.4-kilobase conjugative transposon originally identified on the chromosome of Streptococcus faecalis DS16. The transposon has been cloned in Escherichia coli on plasmid vectors, where it expresses tetracycline resistance; it can be reintroduced into S. faecalis via protoplast transformation.
E, Senghas +4 more
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Protein conjugation with genetically encoded unnatural amino acids [PDF]
Current Opinion in Chemical Biology, 2013 The site-specific incorporation of unnatural amino acids with orthogonal chemical reactivity into proteins enables the synthesis of structurally defined protein conjugates. Amino acids containing ketone, azide, alkyne, alkene, and tetrazine side chains can be genetically encoded in response to nonsense and frameshift codons.
Chan Hyuk, Kim +2 more
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Genetic drift suppresses bacterial conjugation in spatially structured populations [PDF]
Biophysical Journal, 2014 ABSTRACTConjugation is the primary mechanism of horizontal gene transfer that spreads antibiotic resistance among bacteria. Although conjugation normally occurs in surface-associated growth (e.g., biofilms), it has been traditionally studied in well-mixed liquid cultures lacking spatial structure, which is known to affect many evolutionary and ...
Freese, PD +3 more
openaire +5 more sources
GENETIC ASPECTS OF INDIRECT HYPERBILIRUBINAEMIA IN NEWBORNS
Slovenska pediatrija, 2022 Indirect hyperbilirubinaemia is a common finding in the neonatal period. There are numerous causes of neonatal indirect hyperbilirubinemia, from excessive bilirubin production, impaired hepatic bilirubin uptake or bilirubin conjugation and increased ...
Katja Jarc Georgiev, Manca Velkavrh
doaj +1 more source
Communications Biology, 2023 Bacterial conjugation is a major horizontal gene transfer mechanism. While the functions encoded by many conjugative plasmids have been intensively studied, the contribution of recipient chromosome-encoded genes remains largely unknown. Here, we analyzed
Nancy Allard +4 more
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Genome-Wide Association Study Reveals Host Factors Affecting Conjugation in Escherichia coli
Microorganisms, 2022 The emergence and dissemination of antibiotic resistance threaten the treatment of common bacterial infections. Resistance genes are often encoded on conjugative elements, which can be horizontally transferred to diverse bacteria.
Laetitia Van Wonterghem +6 more
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mSystems, 2020 The rapid horizontal transmission of antibiotic resistance genes on conjugative plasmids between bacterial host cells is a major cause of the accelerating antibiotic resistance crisis.
Hanna Alalam +14 more
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Transfer of antibiotic resistance in Staphylococcus aureus [PDF]
, 2017 Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera.
Haaber, Jakob +2 more
core +1 more source