Population gene introgression and high genome plasticity for the zoonotic pathogen Streptococcus agalactiae [PDF]
The influence that bacterial adaptation (or niche partitioning) within species has on gene spillover and transmission among bacteria populations occupying different niches is not well understood.
Abbott +124 more
core +2 more sources
Development of a Gene Replacement Method for the Filamentous Bacterium Leptothrix cholodnii SP-6
Genetic strategies such as gene disruption and fluorescent protein tagging largely contribute to understanding the molecular mechanisms of biological functions in bacteria.
Tatsuki Kunoh +5 more
doaj +1 more source
Genetic organization of plasmid R1162 DNA involved in conjugative mobilization [PDF]
DNA involved in the mobilization of broad-host-range plasmid R1162 was localized to a region of 2.7 kilobases within coordinates 3.4 to 6.1 kilobases on the R1162 map. By examining the transfer properties of plasmids containing cloned fragments of DNA from within this region, we showed that at least four trans-active products and a cis-active site ...
M A, Brasch, R J, Meyer
openaire +2 more sources
Nonomuraea gerenzanensis (N. gerenzanensis) is known for its ability to biosynthesize A40926, the precursor of the glycopeptide antibiotic (GPA) Dalbavancin.
Shi shi +6 more
doaj +1 more source
Monitoring Bacterial Conjugation by Optical Microscopy
Bacterial conjugation is the main mechanism for horizontal gene transfer, conferring plasticity to the genome repertoire. This process is also the major instrument for the dissemination of antibiotic resistance genes. Hence, gathering primary information
Gerardo Carranza +5 more
doaj +1 more source
Inhibition of hepatitis C virus RNA replication by ISG15 does not require its conjugation to protein substrates by the HERC5 E3 ligase [PDF]
Chronic infection of the liver by hepatitis C virus (HCV) induces a range of host factors including IFN-stimulated genes such as ISG15. ISG15 functions as an antiviral factor that limits virus replication. Previous studies have suggested that ISG15 could
Bamford, Connor G.G. +3 more
core +2 more sources
Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications [PDF]
Conjugation of ubiquitin to proteins (ubiquitylation) has emerged to be one of the most crucial post-translational modifications controlling virtually all cellular processes.
Fulda, Simone +2 more
core +2 more sources
Site-specific chemical protein conjugation using genetically encoded aldehyde tags [PDF]
We describe a method for modifying proteins site-specifically using a chemoenzymatic bioconjugation approach. Formylglycine generating enzyme (FGE) recognizes a pentapeptide consensus sequence, CxPxR, and it specifically oxidizes the cysteine in this sequence to an unusual aldehyde-bearing formylglyine.
David, Rabuka +4 more
openaire +2 more sources
Background Conjugation is a major type of horizontal transmission of genes that involves transfer of a plasmid into a recipient using specific conjugation machinery, which results in an extended spectrum of bacterial antibiotics resistance.
Yang Liu +6 more
doaj +1 more source
Models for Gut-Mediated Horizontal Gene Transfer by Bacterial Plasmid Conjugation
The emergence of new antimicrobial resistant and virulent bacterial strains may pose a threat to human and animal health. Bacterial plasmid conjugation is a significant contributor to rapid microbial evolutions that results in the emergence and spread of
Logan C. Ott +3 more
doaj +1 more source

