Results 131 to 140 of about 670,162 (341)
Genomic Characterization of a Clinical NDM-1-Producing Klebsiella michiganensis from Brazil
MicroorganismsPublic health faces daily challenges due to increasing reports of pathogenic microorganisms with new antimicrobial resistance. Klebsiella michiganensis, an emerging pathogen, poses difficulty in its identification using conventional techniques.
Amanda Yaeko Yamada +10 more
doaj +1 more source
Regular Objects, Multiplicative Unitaries and Conjugation
, 2002 The notion of left (resp. right) regular object of a tensor C*-category equipped with a faithful tensor functor into the category of Hilbert spaces is introduced. If such a category has a left (resp.
Pinzari, Claudia, Roberts, John E.
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Regulation of Gram-Positive Conjugation
Frontiers in Microbiology, 2019 Type IV Secretion Systems (T4SSs) are membrane-spanning multiprotein complexes dedicated to protein secretion or conjugative DNA transport (conjugation systems) in bacteria.
V. Kohler, W. Keller, E. Grohmann
semanticscholar +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Understanding Cross-Conjugation for Organic Electronics [PDF]
, 2019 Comunicación a congresopi-Conjugated organic molecules have been the focus of interest since they have been probed as potential semiconducting materials,[1] suitable for replacing the widely used silicon technologies.
Medina, Samara, Medina, Samara
core
Conjugation on reddening sequences and conjugation difference
Journal of AlgebraWe describe the conjugation of the reddening sequence according to the formula of $c$-vectors with respect to changing the initial seed. As applications, we extend the Rotation Lemma, the Target before Source Theorem, and the mutation invariant property of the existence of reddening sequences to totally sign-skew-symmetric cluster algebras. Furthermore,
Siyang Liu, Jie Pan
openaire +3 more sources
Bisphosphonate conjugation for bone specific drug targeting
Bone Reports, 2018 Bones provide essential functions and are sites of unique biochemistry and specialized cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has presented difficulties in the past, and improved delivery of drugs to bone ...
Kristen Farrell +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source