Results 291 to 300 of about 670,162 (341)
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2005
Molecular conjugates are nanometer-sized entities consisting of synthetic materials (lipids, polycations, targeting agents, and so on) and nucleic acids. These composites are delivery vehicles that function to provide the transport of nucleic acids to sites of action. Recently, great progress has been made in the construction of these nonviral delivery
Jeremy, Heidel +2 more
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Molecular conjugates are nanometer-sized entities consisting of synthetic materials (lipids, polycations, targeting agents, and so on) and nucleic acids. These composites are delivery vehicles that function to provide the transport of nucleic acids to sites of action. Recently, great progress has been made in the construction of these nonviral delivery
Jeremy, Heidel +2 more
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Expert Opinion on Biological Therapy, 2020
Introduction: We discuss chemical conjugation strategies for antibody-drug conjugates (ADCs) from an industrial perspective and compare three promising chemical conjugation technologies to produce site-specific ADCs.
Yutaka Matsuda, B. Mendelsohn
semanticscholar +1 more source
Introduction: We discuss chemical conjugation strategies for antibody-drug conjugates (ADCs) from an industrial perspective and compare three promising chemical conjugation technologies to produce site-specific ADCs.
Yutaka Matsuda, B. Mendelsohn
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Annals of the New York Academy of Sciences, 2013
There has been considerable effort expended in the investigation of the potential of siderophore conjugates of antibiotics to circumvent the permeability barrier imposed by the outer membrane of Gram‐negative bacteria. There is also a small group of natural conjugates, the sideromycins.
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There has been considerable effort expended in the investigation of the potential of siderophore conjugates of antibiotics to circumvent the permeability barrier imposed by the outer membrane of Gram‐negative bacteria. There is also a small group of natural conjugates, the sideromycins.
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Dihydroazulene–Buckminsterfullerene Conjugates
The Journal of Organic Chemistry, 2012The dihydroazulene (DHA)/vinylheptafulvene (VHF) photo/thermoswitch has recently attracted interest as a molecular switch for molecular electronics. In this field, Buckminsterfullerene, C(60), has been shown to be a useful anchoring group for adhering a molecular wire to an electrode.
Santella, Marco +6 more
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Amphiphilic Peptide–Polymer Conjugates with Side‐Conjugation
Macromolecular Rapid Communications, 2011AbstractPolymers conjugated to the exterior of a protein mediate its interactions with surroundings, enhance its processability and can be used to direct its macroscopic assemblies. Most studies to date have focused on peptide–polymer conjugates based on hydrophilic polymers.
Nikhil, Dube +3 more
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tRNA conjugation with folic acid-chitosan conjugates
International Journal of Biological Macromolecules, 2017The conjugation of tRNA with folic acid-chitosan conjugates was studied, using multiple spectroscopic methods and transmission electron microscopy (TEM). Thermodynamic analysis ΔH -14 to -10 (KJMol-1) and ΔS 14 to -1 (JMol-1, K-1) showed tRNA-folic acid-chitosan bindings occur via H-bonding, hydrophobic and van der Waals contacts.
P, Chanphai, H A, Tajmir-Riahi
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Food Chemistry, 2018
To help produce hypoallergenic food, this study investigated reducing the allergenicity and improving the functional properties of bovine β-lactoglobulin (βLG) by covalent conjugation with (-)-epigallo-catechin 3-gallate (EGCG) and chlorogenic acid (CA).
Xuli Wu +7 more
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To help produce hypoallergenic food, this study investigated reducing the allergenicity and improving the functional properties of bovine β-lactoglobulin (βLG) by covalent conjugation with (-)-epigallo-catechin 3-gallate (EGCG) and chlorogenic acid (CA).
Xuli Wu +7 more
semanticscholar +1 more source
Conjugation Equation for Quaternionic Conjugation Spaces
Russian Journal of Mathematical PhysicsThe complex projective space \(\mathbb C\mathrm P^n\) has an obvious involution \(\tau\) given via complex conjugation. It is not hard to see that the subspace \((\mathbb C\mathrm P^n)^\tau\) of points fixed by \(\tau\) is homeomorphic to \(\mathbb R\mathrm P^n\).
Kryazhev, A. +2 more
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Conjugation Site Analysis of Lysine-Conjugated ADCs
2019Lysine-conjugated antibody-drug conjugates (ADCs) are formed by attaching cytotoxic drugs to reactive lysine residues of monoclonal antibodies (mAbs) through chemical linkers. During production, the payloads are conjugated nonspecifically to lysine residues in mAbs, resulting in a heterogeneous mixture of ADCs with both different number and conjugation
Hua, Sang +5 more
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Conjugate Maps and Conjugate Duality
1985This paper considers conjugate duality in multiobjective optimization, in which minimality (efficiency, noninferiority, or Pareto optimality) is a natural solution concept. First, conjugate maps and subgradients are defined for vector-valued functions and point-to-set maps.
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