Results 171 to 180 of about 2,125,845 (252)

SCORTEN in Contrast: Two Cases of SJS/TEN Overlap With Divergent Outcomes Highlighting the Role of Renal Dysfunction

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Stevens‐Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) overlap is a rare, life‐threatening mucocutaneous reaction typically induced by medications. Reports from Central America remain scarce. We present two contrasting cases of SJS/TEN overlap from Nicaragua.
Marvin Alfaro, Virgilio Blandón, Miguel Borge   +2 more
wiley   +1 more source

Carbamazepine‐Induced Stevens‐Johnson Syndrome/Toxic Epidermal Necrolysis Overlap With Severe Ocular and Oral Involvement: A Pediatric Case Report From Uganda

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT We report a case of carbamazepine‐induced Stevens‐Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) overlap in an 11‐year‐old Ugandan boy who presented with fever, facial swelling, ocular redness with photophobia, painful oral ulceration, and widespread epidermal detachment involving more than 10% of the body surface area.
Abdisalam Ahmed Sandeyl, Abdisamad Guled Hersi, Zakarie Abdullahi Hussein, Mohamed Farah Ismail, Abdullahi Ali Bulle, Mamoun Nasr   +5 more
wiley   +1 more source

An In Vitro and In Vivo Assessment of the Anti‐Breast Cancer Activity of Erythrina excelsa Baker (Fabaceae) Bark Extracts

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Breast cancer remains a topic of interest due to its high mortality rate among Cameroonian women. The barks of Erythrina excelsa are traditionally used for medicinal purposes in the management of various conditions including cancer.
Jonas Walantini, Marius Trésor Kemegne Sipping, Merline Nguedia Ymele, Roland Nhouma Rebe, Joël Abel Gbaweng Yaya, Derek Tantoh Ndinteh, Dieudonné Njamen, Stéphane Zingue   +7 more
wiley   +1 more source

Results From a Phase 2, Open‐Label Study Evaluating the Safety, Tolerability, and Effect on Ataxia of GLM101 in Three Adult Patients With PMM2‐CDG

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACT Phosphomannomutase 2 congenital disorder of glycosylation (PMM2‐CDG) is a rare, autosomal recessive disease caused by PMM2 deficiency, which impairs conversion of mannose‐6‐phosphate into mannose‐1‐phosphate (M1P) and disrupts N‐linked glycosylation.
Mercedes Serrano, Florencia Epifani, Rose Marino, Peter McWilliams   +3 more
wiley   +1 more source

Clinical Manifestations Associated With RT‐PCR–Confirmed Zika Virus Infection Among Adults With Acute Rash in the Brazilian Amazon: A Cross‐Sectional Study

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Zika virus (ZIKV) infection remains a diagnostic challenge in regions where multiple arboviruses co‐circulate, particularly when laboratory testing is limited. Identifying distinguishing clinical features is therefore relevant for early case recognition. We conducted a cross‐sectional study including 1124 adults presenting with acute exanthema
Djane Clarys Baía‐da‐Silva, Yanka Karolinna Batista Rodrigues, Karolina Jeaneth Solórzano‐Chavarría, Luís Felipe Alho da Silva, Alexandre Vilhena Silva‐Neto, Luiz Henrique Gonçalves Maciel, Maria Paula Gomes Mourão, Marcia da Costa Castilho, Camila Botto‐Menezes   +8 more
wiley   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, Volume 15, Issue 3, Page 176-193, September 2026.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

Sequence‐encoded determinants drive distinct early aggregation pathways and different structural outcomes in PNT1 fibrils across Henipavirus members

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Protein aggregation is increasingly recognized as a biologically relevant process in viral proteins, yet the molecular determinants governing such phenomena remain poorly understood. Intrinsically disordered proteins (IDPs) are ubiquitous in viral proteomes, where conformational plasticity not only enables functional diversity but also permits
Harshita Sawdekar, Julien Mignon, Frank Gondelaud, Anuja Walimbe, Samrat Mukhopadhyay, Joseph Chamieh, Sonia Longhi   +6 more
wiley   +1 more source

The Changing Landscape of Hantavirus Infections: A Narrative Review of Epidemiology, Pathogenesis, and Countermeasures

Reviews in Medical Virology, Volume 36, Issue 5, September 2026.
ABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
Francesco De Maria, Francesco Branda, Giancarlo Ceccarelli, Fabio Scarpa, Massimo Ciccozzi, Alessandro Russo   +5 more
wiley   +1 more source

Effects of Exercise on Ocular Parameters and Oxidative Stress Biomarkers in Saliva and Tear Fluid of Horses

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Submaximal exercise induced measurable oxidative responses in saliva and tear fluid of horses, while ocular parameters remained largely stable except for a mild reduction in tear secretion. Saliva and tear fluid may serve as practical, minimally invasive matrices for monitoring exercise‐associated physiological and oxidative responses in horses ...
Ferda Turgut, Latif Emrah Yanmaz, Omer Tarik Orhun, Betul Apaydin Yildirim, Yakup Kocaman, Mumin Gokhan Senocak, Taner Arslan, Vildan Aslan Canatan   +7 more
wiley   +1 more source

Surviving Fibroblasts After Treatment With Mitomycin C Exhibit SASP‐Like Phenotype After Glaucoma Filtration Surgery

Aging Cell, Volume 25, Issue 9, September 2026.
Transcriptomic analysis using a rabbit glaucoma filtration surgery model, combined with in vitro experiments on human conjunctival fibroblasts, demonstrates that mitomycin C induces a senescence‐associated secretory phenotype (SASP)‐like state. These SASP‐like fibroblasts were selectively eliminated by the specific senolytic agent, highlighting their ...
Akitoshi Kimura, Tomokazu Fujimoto, Satoshi Iraha, Kei‐Ichiro Yasunaga, Miyuki Inoue‐Mochita, Naofumi Funagura, Shunsuke Tanigawa, Daisuke Kurotaki, Tomoaki Koga, Fumika Watanabe‐Kitamura, Utako Tsutsumi‐Kuroda, Mitsuyoshi Nakao, Toshihiro Inoue   +12 more
wiley   +1 more source