Results 171 to 180 of about 44,209 (273)

Investigation Into the Collection and Isolation Workflows of Extracellular Vesicles From Tears

open access: yesJournal of Extracellular Biology, Volume 5, Issue 7, July 2026.
Sampling and isolation methodology shapes tear extracellular vesicle (tEV) composition, influencing housekeeping gene stability, tetraspanin expression, and cytokine levels. Contact lenses and Schirmer Strips provide complementary molecular signatures, while ExoQuick and ultracentrifugation differ in vesicle yield and surface properties.
Nikolay Boychev   +4 more
wiley   +1 more source

An Explainable Machine Learning Model for Early Prediction of Incident Myocardial Injury in Patients With Severe Fever With Thrombocytopenia Syndrome

open access: yesJournal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT This study aimed to develop an explainable machine learning–based model to enable early prediction of incident myocardial injury during hospitalization among patients with severe fever with thrombocytopenia syndrome (SFTS). This multicenter retrospective cohort study included and analyzed clinical data from 1,088 patients with SFTS who were ...
Xiang Li   +11 more
wiley   +1 more source

Multiomics Identification and Validation of an Integrin–Extracellular Matrix Network Driving Respiratory Syncytial Virus‐Induced Lung Injury and Repair

open access: yesMedComm, Volume 7, Issue 7, July 2026.
This graphical abstract depicts the dynamic progression from acute lung inflammation to fibrotic repair following RSV infection. Multiomics analysis uncovers a central regulatory network coordinating key pathways including coagulation, extracellular matrix deposition, integrin signaling, and cytoskeletal reorganization.
Lili Zhou   +12 more
wiley   +1 more source

The Clinical Accuracy of Diagnosing Chronic Conjunctival Lesions and the Importance of Limbal Involvement in Suspecting Malignancy. [PDF]

open access: yesJ Clin Med
Élő Á   +10 more
europepmc   +1 more source

Optimal Weighted Tests for Replication Studies and the ‘Two‐Trials Rule’ With Multiple Hypotheses

open access: yesStatistics in Medicine, Volume 45, Issue 15-17, July 2026.
ABSTRACT Replication studies for scientific research are an important part of ensuring the reliability and integrity of experimental findings. In the context of clinical trials, the concept of replication has been formalized by the “two‐trials” rule, where two pivotal studies are required to show positive results before a drug can be approved.
David S. Robertson, Thomas Jaki
wiley   +1 more source

Sedative Effects of Dexmedetomidine and Ketamine or Dexmedetomidine and Midazolam on Tear Production, Ocular Perfusion Pressure and Pupil Diameter in Rabbits

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Sedative effects of intramuscular injection of dexmedetomidine and ketamine or dexmedetomidine and midazolam on tear production (TP), ocular perfusion pressure (OPP) and pupillary diameter (PD) in two groups of seven male New Zealand rabbits (G1 and G2, respectively).
Maryam Mohammadzadeh   +2 more
wiley   +1 more source

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