ABSTRACT Ibuprofen is the most commonly used NSAID; however, its short biological half‐life, reflected in the short duration of pain relief, limits the comfortableness of its usage. This study evaluated the pharmacokinetic properties of a newly developed biphasic ibuprofen 400 mg immediate‐release/sustained‐release (IR/SR) modified‐release tablets ...
Ludmila Kvapilová +6 more
wiley +1 more source
An unusual presentation of meningococcal meningitis. [PDF]
Khan AZ, Fineide F, Utheim TP.
europepmc +1 more source
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes +2 more
wiley +1 more source
European S2k guidelines on management of autoimmune blistering diseases in children and adolescents
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda +31 more
wiley +1 more source
Polyprenyl immunostimulant treatment during experimental feline herpesvirus-1 infection is associated with reduced ocular disease after conjunctival rechallenge. [PDF]
Heidel RE +5 more
europepmc +1 more source
Biomarkers for therapeutic response and adverse outcomes in atopic dermatitis: A systematic review
This review assessed 52 biomarkers predicting systemic therapy response and adverse events in atopic dermatitis. Most studies focused on dupilumab, and findings were inconsistent. IgE and eosinophils were largely non‐predictive, though elevated eosinophils and LDH sometimes indicated poorer outcomes.
Eva Hilger +11 more
wiley +1 more source
Efficacy and safety of cyclosporine 1% eye drops for the treatment of pediatric blepharokeratoconjunctivitis. [PDF]
Masini M +10 more
europepmc +1 more source
Psychogenic polydipsia in dogs – a review of pathogenesis, diagnosis and treatment
Polyuria and polydipsia represent a common clinical presentation in dogs and may result from numerous disorders affecting different body systems. Compulsive water consumption is characteristic of psychogenic polydipsia, a primary polydipsia disorder rooted in neurologic, behavioural or environmental factors.
G. Pavlovsky
wiley +1 more source
A multicenter retrospective study of non-traumatic corneal perforation: etiology, disease course, clinical manifestations, and treatment strategies. [PDF]
Xie H +29 more
europepmc +1 more source

