Results 101 to 110 of about 110,850 (216)

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, Volume 104, Issue 6, Page 604-615, September 2026.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Mediastinal neuroblastoma causing Horner's syndrome in a 7-year-old child: a case report

Journal of Pediatric Surgery Case Reports
Introduction: Peripheral neuroblastic tumors comprise a spectrum of neoplasms (neuroblastoma, ganglioneuroblastoma, ganglioneuroma) that primarily arise from the sympathoadrenal lineage and can cause variety of symptoms.
Alicija Šavareikaitė, Paulius Valatka
doaj   +1 more source

Powering Neurology Drug Development Trials to Reduce False Negative Results

Clinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Sensitive and reliable measurement of therapeutic outcomes in neurology drug trials remains challenging. Clinical rating scales and their total scores are often considered the gold standard and used as primary efficacy endpoints in studies because of their acceptance by the clinical community and regulators.
Hiromasa Mori, Stig Johan Wiklund, Vikram Ramanarayanan, Fatta B. Nahab   +3 more
wiley   +1 more source

Rare neoplasms

, 2015
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
CIARAVINO, VALENTINA, MALAGO', Roberto, Capelli, Paola, DE ROBERTIS LOMBARDI, Riccardo, PEDICA, Federica, POZZI MUCELLI, Roberto   +5 more
core  

Tumores de los anexos oculares Ocular adnexa tumors

Revista Cubana de Oftalmología, 2001
Se realizó un estudio retrospectivo de 211 pacientes, operados por presentar alguna tumoración de los anexos, con confirmación histológica en el período comprendido entre enero de 1993 hasta diciembre de 1997.
Clara G. Gómez Cabrera, Isaías Toro Toloza, Lázaro Vigoa Aranguren   +2 more
doaj  

Neural modulation of ocular immunity: Exploring a sympathetic‐macrophage neuroimmune link in the human ciliary body

Journal of Anatomy, Volume 249, Issue 3, Page 565-577, September 2026.
Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou, Claire Mackaaij, Mark van Zijverden, Hendrik A. Messal, Jeannette Ossewaarde‐van Norel, Ronald L. A. W. Bleys, Cindy G. J. Cleypool   +6 more
wiley   +1 more source

Zebrafish as a practical and convenient model for the study of photodynamic and photothermal therapy of solid tumors: A scoping review

Photochemistry and Photobiology, Volume 102, Issue 5, Page 1060-1078, September/October 2026.
Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson, Alexander Fiorentino, Brian W. Booth, Valery Bliznyuk, Diana Ivankovic, Luigi Boccuto   +5 more
wiley   +1 more source

Conjunctival Flora in Diabetic and Nondiabetic Individuals

, 2015
Objectives: To evaluate the conjunctival bacterial flora in diabetic patients and nondiabetic subjects. Materials and Methods: Fifty-three diabetic patients and 43 nondiabetic healthy individuals were included in the study.
Mehmet Balcı, Hasan Ali Bayhan, Mehmet Adam   +2 more
core   +1 more source

Ocular melanoma-when you have seen one, you have not seen them all: a clinical outcome study from the Surveillance, Epidemiology and End Results (SEER) database (1973–2012)

Clinical Ophthalmology, 2017
Krishnaraj Mahendraraj,1 Sneha Shrestha,1 Christine SM Lau,1,2 Ronald S Chamberlain1–4 1Department of Surgery, Saint Barnabas Medical Center, Livingston, NJ, USA; 2Saint George’s University School of Medicine, Grenada, West Indies ...
Mahendraraj K, Shrestha S, Lau CSM, Chamberlain RS   +3 more
doaj  

Zygomatic Sialadenitis as a Rare Cause of Exophthalmos in a Dog

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective To describe the clinical presentation, diagnostic findings, and surgical management of zygomatic sialadenitis associated with retrobulbar disease in a dog following extensive dental extractions. Animals Studied A 10‐year‐old spayed female Cavalier King Charles Spaniel.
Katrina E. V. Jones, Manabu Kurihara, Hans D. Westermeyer, Danielle Meritet   +3 more
wiley   +1 more source