Results 61 to 70 of about 368,835 (244)

Xeroderma Pigmentosum [PDF]

, 2011
Xeroderma pigmentosum (XP) is defined by extreme sensitivity to sunlight, resulting in sunburn, pigment changes in the skin and a greatly elevated incidence of skin cancers.
Lehmann, Alan R, McGibbon, David, Stefanini, Miria   +2 more
core   +3 more sources

Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients

The Laryngoscope, EarlyView.
ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma, Sushanth Neerumalla, Ali Baird, Russell A. Whitehead, Peter Filip, Bobby A. Tajudeen, Pete S. Batra, Peter Papagiannopoulos   +7 more
wiley   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source

Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano, Vito Romano, Alejandra Daruich, Giulio Ferrari, Matthieu Robert, Francesco Semeraro, Neil Lagali, Dominique Bremond‐Gignac, the ANIRIDIA‐NET Clinical Guidelines Working Group, Miriam Barbany, Claus Cursiefen, Stefano Ferrari, Francisco Figueiredo, Christina Grupcheva, Jesper Hjortdal, Elke Kreps, Erlend Landsend, Laura Mauring, Hilde Pedersen, Nora Szentmáry, Bogumil Wowra, the Aniridia‐Europa and Geniris Working Group, Sophie Valleix, Juan Álvarez de Toledo, James Lauderdale, Tor Paaske Utheim, Paolo Rama   +26 more
wiley   +1 more source

Personalized treatment concepts in extraocular cancer

Advances in Ophthalmology Practice and Research
Background: The periocular skin is neoplasms-prone to various benign and malignant. Periocular malignancies are more aggressive and challenging to cure and repair than those in other skin areas. In recent decades, immunotherapy has significantly advanced
Sitong Ju, Alexander C. Rokohl, Yongwei Guo, Ke Yao, Wanlin Fan, Ludwig M. Heindl   +5 more
doaj   +1 more source

Ocular Surface Squamous Neoplasia in Xeroderma Pigmentosum [PDF]

, 2013
Xeroderma pigmentosum (XP) is a rare genetic disorder associated with multiple oculocutaneous and neurological manifestations. It occurs due to deficiency of the enzymes responsible for repairing ultraviolet radiation-induced DNA damage.
Ajay R Kamath, Gurudutt M Kamath, Manjunath M Kamath, Rajesh R Nayak, Roopashree, Susan D'Souza   +5 more
core   +1 more source

Melanosis in eyelid margin with malignancy suspect: case report [PDF]

, 2009
A case of a patient with an irregular pigmented lesion of the lower eyelid margin simulating malignant tumor, which was treated based on the results of impression cytology and diagnosed by histopathological study is presented.
Barros, Jeison de Nadai, Cvintal, Tadeu, Oliveira, Claudia Akemi Shiratori de, Schellini, Silvana Artioli, Souza, Simone de Biagi   +4 more
core   +2 more sources

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

p16 Expression Correlates with Invasive Ocular Surface Squamous Neoplasms in HIV-Infected Mozambicans

Ocular Oncology and Pathology, 2019
Background: p16 immunohistochemistry is widely used to diagnose human papillomavirus (HPV)-related squamous neoplasms of cervix, anogenital, head, and neck tissues.
C. Carrilho, Chau Miu, Yeji Kim, S. Karki, Alexandra Balmaceda, Bindu S Challa, S. Diamond, Eliane C S Monteiro, Evelia Marole, C. Lorenzoni, Yolanda Zambujo, Yu-Tseung Liu, R. Schooley, Jonathan H. Lin   +13 more
semanticscholar   +1 more source

Primary cardiac T‐cell rich large B‐cell lymphoma causing aortic stenosis with metastasis in a Warmblood

Equine Veterinary Education, EarlyView.
Summary An 18‐year‐old Warmblood mare was presented to the Royal Veterinary College Equine Referral Hospital for investigation of progressive periocular and facial swelling, weight loss and tachycardia. Physical examination additionally identified bilateral pansystolic (grade 5/6 basilar left‐sided, 2/6 right‐sided), cardiac murmurs, submandibular ...
S. E. Talbot, F. Z. X. Lean, H. M. Martineau, B. Dunkel, J. Reed   +4 more
wiley   +1 more source