Results 101 to 110 of about 5,986,669 (282)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Constructing a CDS-Based Network Backbone for Data Collection in Wireless Sensor Networks

International Journal of Distributed Sensor Networks, 2013
Data collection is one of the most important operations in wireless sensor networks. Currently, many researches focus on using a connected dominating set to construct a virtual backbone for data collection in WSNs.
Xiaoyan Kui, Yu Sheng, Huakun Du, Junbin Liang   +3 more
doaj   +1 more source

A Distributed Algorithm for Minimum Distance-k Domination in Trees

Journal of Graph Algorithms and Applications, 2015
While efficient algorithms for finding minimal distance-k dominating sets exist, finding minimum such sets is NP-hard even for bipartite graphs. This paper presents a distributed algorithm to determine a minimum (connected) distance-k dominating ...
Volker Turau, Sven Köhler
doaj   +1 more source

On Constructing Strongly Connected Dominating and Absorbing Set in 3-Dimensional Wireless Ad Hoc Networks

Complexity, 2020
In a wireless ad hoc network, the size of the virtual backbone (VB) is an important factor for measuring the quality of the VB. The smaller the VB is, the less the overhead caused by the VB.
Jiarong Liang, Meng Yi, Weiguang Zhang, Yanyan Li, Xinyu Liang, Bin Qin   +5 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

2-connected graphs with small 2-connected dominating sets

Discrete Mathematics, 2003
The main result of the paper is the following. Let \(G\) be a \(2\)-connected graph with \(n\) vertices and minimum degree \(\delta\). Then \(\gamma_2 \leq n(\ln(\delta)/\delta)(1+o_{\delta}(1))\), where \(\gamma_2\) is the minimum size of a \(2\)-connected dominating set of \(G\) and \(o_{\delta}(1)\) denotes a function that tends to 0 as \(\delta ...
Yair Caro, Raphael Yuster
openaire   +2 more sources

Open-independent, open-locating-dominating sets

Electronic Journal of Graph Theory and Applications, 2017
A distinguishing set for a graph G = (V, E) is a dominating set D, each vertex $v \in D$ being the location of some form of a locating device, from which one can detect and precisely identify any given "intruder" vertex in V(G).
Suk J. Seo, Peter J. Slater
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source