Results 111 to 120 of about 5,986,669 (282)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Two Short Proofs on Total Domination

open access: yesDiscussiones Mathematicae Graph Theory, 2013
A set of vertices of a graph G is a total dominating set if each vertex of G is adjacent to a vertex in the set. The total domination number of a graph Υt (G) is the minimum size of a total dominating set.
Bickle Allan
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

A new distributed weighted connected dominating set algorithm for WSNs

open access: yes, 2018
In this paper, a novel distributed weighted minimal connected dominating set algorithm is proposed. The new algorithm consists of two phases. In the first phase the dominating set is constructed by selecting nodes having low weight and connecting more ...
Haytaoğlu, Elif, Tosun, Mustafa
core   +1 more source

Wireless sensor network design for smart grids and Internet of things for ambient living using cross-layer techniques

open access: yesInternational Journal of Distributed Sensor Networks, 2019
Due to the increased demand of wireless sensor networks for their characteristics like low energy consumption, robustness, and low cost in several demanding and complex applications like smart grid, health and safety, traffic and weather updates, there ...
Jaffar Ali   +5 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The planar connected face-dominating set problem. (c2015)

open access: yes, 2015
Includes bibliographical references (leaves 39-40).In the Planar Connected Face-Dominating Set problem, we are given a plane graph G and asked to find a connected subgraph T of minimum weight, or order, such that the boundary of every face of G contains ...
Hage-Ali, Dina Y.
core   +1 more source

On the global offensive alliance in unicycle graphs

open access: yesAKCE International Journal of Graphs and Combinatorics, 2018
For a graph , a set is a dominating set if every vertex in has at least a neighbor in . A dominating set is a global offensive alliance if for each vertex in at least half the vertices from the closed neighborhood of are in The domination number is the ...
Mohamed Bouzefrane, Saliha Ouatiki
doaj   +1 more source

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