Results 101 to 110 of about 1,217,256 (282)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
مجلة بغداد للعلوم, 2019 The aim of this article is to introduce a new definition of domination number in graphs called hn-domination number denoted by . This paper presents some properties which show the concepts of connected and independent hn-domination.
Omran et al.
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Some results on the independence number of connected domination critical graphs
AKCE International Journal of Graphs and Combinatorics, 2018 A --critical graph is a graph with connected domination number and for any pair of non-adjacent vertices and of . Let and be respectively the clique number and the independence number of a graph.
P. Kaemawichanurat, T. Jiarasuksakun
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Connected Domination Critical Graphs [PDF]
, 2015 This thesis investigates the structure of connected domination critical graphs. The characterizations developed provide an important theoretical framework for addressing a number of difficult computational problems in the areas of operations research ...
Kaemawichanurat, Pawaton
core +1 more source
Connected Partitions via Connected Dominating Sets
CoRRThe classical theorem due to Győri and Lovász states that any $k$-connected graph $G$ admits a partition into $k$ connected subgraphs, where each subgraph has a prescribed size and contains a prescribed vertex, as long as the total size of target subgraphs is equal to the size of $G$.
Niklanovits, Aikaterini +3 more
openaire +5 more sources
Connected Dominating Sets [PDF]
, 2009 Wireless sensor networks (WSNs) are now widely used in many applications. However, routing in WSNs is very challenging due to the inherent characteristics that distinguish these networks from other wireless networks. The concept of hierarchical routing is widely used to perform energy-efficient routing in WSNs.
Yiwei Wu, Yingshu Li
openaire +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Domination Analysis of Greedy Heuristics For The Frequency Assignment Problem [PDF]
, 2003 We introduce the greedy expectation algorithm for the fixed spectrum version of the frequency assignment problem. This algorithm was previously studied for the travelling salesman problem.
Noble, SD +6 more
core +1 more source