Results 141 to 150 of about 7,398 (287)
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Connective Dominating In SuperHyperGraphs
, 2023 “Book #177” [ADDRESSED CITATION] [HG177b] Henry Garrett, “Connective Dominating In SuperHyperGraphs”. Dr. Henry Garrett, 2023 (doi: 10.5281/zenodo.8051368). @googlebooks:https://books.google.com/books/about?id=- @GooglePlay:https://play.google.com/store/books/details?id=- @ResearchGate: https://www.researchgate.net/publication/- @WordPress: https ...
openaire +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Tractable connected domination for restricted bipartite graphs (extended abstract)
, 2013 Finding a minimum connected dominating set (connected domination) is known-complete for chordal bipartite graphs, but tractable for convex bipartite graphs.
Xu, Ke +5 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
On the doubly connected domination number of a graph
Open Mathematics, 2006 Cyman Joanna +2 more
doaj +1 more source
Connected hop domination in graphs under some binary operations
, 2018 Let [Formula: see text] be a simple graph. A hop dominating set [Formula: see text] is called a connected hop dominating set of [Formula: see text] if the induced subgraph [Formula: see text] of [Formula: see text] is connected. The smallest cardinality
Yamilita M. Pabilona, Helen M. Rara
core +1 more source