Results 151 to 160 of about 7,398 (287)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
BiomathThis study applies a graph-theoretic framework to analyze the structural dynamics of codon networks derived from SARS-CoV-2 spike protein sequences. By employing a dual-level analysis of Minimum Connected Dominating Sets (MCDS) and community structures,
L. Praveenkumar +2 more
doaj +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Neighborhood connected equitable domination in graphs [PDF]
, 2012 Let G = (V,E) be a connected graph, An equitable dominating S of a graph G is called the neighborhood connected equitable dominating set (nced-set) if the induced subgraph Ne(S) is connected The minimum cardinality of a nced-set of G is called the ...
Sivakumar, S., Soner, N. D., Alwardi, A.
core
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source
Total Outer Equitable Connected Domination of a Graph
, 2020 : Let G = (V, E) be a graph. A set D V (G) is equitable dominating set of is outer equitable dominating set if D is equitable dominating and <V -D> is connected graph. The outer equitable connected domination number of G is the minimum cardinality
Deepak G, Jayaprakash M C
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Vertex sequences in graphs [PDF]
Discrete Mathematics Letters, 2021 Teresa W. Haynes, Stephen T. Hedetniemi
doaj +1 more source