Results 91 to 100 of about 232,724 (277)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Edge Roman domination on graphs

open access: yes, 2014
An edge Roman dominating function of a graph $G$ is a function $f\colon E(G) \rightarrow \{0,1,2\}$ satisfying the condition that every edge $e$ with $f(e)=0$ is adjacent to some edge $e'$ with $f(e')=2$.
Chang, Gerard J.   +2 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

The Oriented Diameter of Graphs with Given Connected Domination Number and Distance Domination Number

open access: yesGraphs and Combinatorics
AbstractLet G be a bridgeless graph. An orientation of G is a digraph obtained from G by assigning a direction to each edge. The oriented diameter of G is the minimum diameter among all strong orientations of G. The connected domination number $$\gamma _c(G)$$ γ c
Peter Dankelmann   +2 more
openaire   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Connected-domination triangle graphs and connected neighbourhood numbers

open access: yes, 2016
Дискретная математика и математическая ...
Kartynnik, Y. A., Orlovich, Y. L.
openaire   +1 more source

Triple Connected Domination Number Of A Graph

open access: yes, 2018
{"references": ["1.\tMahadevan G, Selvam A, Paulraj Joseph J, Ayisha B and Subramanian T, Complementary triple connected domination number of a graph, accepted for publication in Advances and Applications inDiscrete Mathematics, ISSN0974-1658(2012). 2.\tMahadevan. G, Selvam Avadayappan, Nagarajan. A, Rajeswari. A, Subramanian.
V. Murugan, N. Rajkumari
openaire   +1 more source

On domination critical graphs with cutvertices having connected domination number 3 [PDF]

open access: yesInternational Mathematical Forum, 2007
A subset of vertices D of a graph G is a dominating set for G if every vertex of G not in D is adjacent to one in D. A dominating set for G is a connected dominating set if it induces a connected subgraph of G. The connected domination number of G, denoted by γc(G), is the minimum cardinality of a connected dominating set.
openaire   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Three domination number and connectivity in graphs

open access: yes, 2015
In a graph G, a vertex dominates itself and its neighbors. A subset S of V is called a dominating set in G if every vertex in V is dominated by at least one vertex in S. The domination number gamma G is the minimum cardinality of a dominating set. A set S subset V is called a double dominating set of a graph G if every vertex in V is dominated by at ...
Mehry, S., Safakish, R.
openaire   +2 more sources

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