Results 111 to 120 of about 9,933,640 (289)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Variants of the Domination Number for Flower Snarks [PDF]
, 2023 We consider the flower snarks, a widely studied infinite family of 3--regular graphs. For the Flower snark $J_n$ on $4n$ vertices, it is trivial to show that the domination number of $J_n$ is equal to $n$. However, results are more difficult to determine
Burdett, Ryan +2 more
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
LOWER BOUNDS FOR THE DOMINATION NUMBER [PDF]
, 2010 In this note, we prove several lower bounds on the domination num-ber of simple connected graphs. Among these are the following: the domination number is at least two-thirds of the radius of the graph, three times the domination number is at least two ...
Waller, Bill +5 more
core +1 more source
Review of Methods and Algorithms for Modelling Transportation Networks Based on Graph Theory
Scientific Journal of Gdynia Maritime University, 2018 One of the best ways of modelling a transport network is to use a graph with vertices and edges. They represent nodes and arcs of such network respectively.
S. Guze
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Three domination number and connectivity in graphs
, 2015 In a graph G, a vertex dominates itself and its neighbors. A subset S of V is called a dominating set in G if every vertex in V is dominated by at least one vertex in S. The domination number gamma G is the minimum cardinality of a dominating set. A set S subset V is called a double dominating set of a graph G if every vertex in V is dominated by at ...
Mehry, S., Safakish, R.
openaire +2 more sources
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source