Results 121 to 130 of about 9,933,640 (289)

Domination Parameters of a Graph and its Complement

Discussiones Mathematicae Graph Theory, 2018
A dominating set in a graph G is a set S of vertices such that every vertex in V (G) \ S is adjacent to at least one vertex in S, and the domination number of G is the minimum cardinality of a dominating set of G.
Desormeaux Wyatt J., Haynes Teresa W., Henning Michael A.   +2 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Connected hop domination in graphs under some binary operations

, 2018
Let [Formula: see text] be a simple graph. A hop dominating set [Formula: see text] is called a connected hop dominating set of [Formula: see text] if the induced subgraph [Formula: see text] of [Formula: see text] is connected. The smallest cardinality
Yamilita M. Pabilona, Helen M. Rara
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Similarities and Differences between the Vertex Cover Number and the Weakly Connected Domination Number of a Graph

, 2017
Similarities and Differences between the Vertex Cover Number and the Weakly Connected Domination Number of a ...
R Trujillo-Rasua (13590631), JA Rodríguez-Velázquez (15888620), M Lemaska (13608169)   +2 more
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Independent and total domination in antiprism graphs from convex polytopes

Mathematics Open
Let [Formula: see text] be a connected graph. Antiprism graphs, defined as the skeletons of antiprism-shaped convex polytopes, consist of [Formula: see text] vertices and [Formula: see text] edges for an n-sided base.
Nasir Ali, R. Arasu, N. Parvathi, K. Marimuthu, Muhammad Imran Qureshi, Hafiz Muhammad Afzal Siddiqui, Aseel Smerat   +6 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Connected domination in Block subdivision graphs of Graphs [PDF]

, 2012
The details of this abstract can be found in the full paper.Key words: Subdivision graph, Block subdivision graph, Connected domination ...
Majeed, Abdul, Muddebihal, M.H.
core