Results 91 to 100 of about 2,175,475 (311)

Chronic complications risk among type 2 diabetes patients with a family history of diabetes

open access: yesChronic Diseases and Translational Medicine, 2023
Dicky L. Tahapary   +9 more
doaj   +1 more source

Connected matchings

open access: yesComputational Geometry
20 pages, 14 figures; preliminary version in EuroCG ...
Oswin Aichholzer   +4 more
openaire   +5 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

American Red Cross Flag, Spanish-American War ca 1898

open access: yes, 1898
This hand-sewn textile(wool) has a halyard rope. It is an American Red Cross flag which was flown on July 1, 1898 at the Battle of San Juan Hill during the Spanish-American War. The flag is rectangular, 108 cm by 180cm. Dr.

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From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Nicotinamide phosphoribosyltransferase (Nampt) in Lateral Hypothalamus Maintains Skeletal Muscle Functions Through Lactate‐Mediated Calcium Signalling in Male Mice

open access: yesJournal of Cachexia, Sarcopenia and Muscle
Background Sarcopenia has become an urgent socioeconomic problem in rapidly aging societies. The pathogenesis of age‐associated sarcopenia is not fully understood and no effective therapeutic strategies have been developed to date.
Takahiro Eguchi   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Human-Machine Connection

open access: yes, 2022
Human-Machine Connection is a 25-minute looped visual narrative presented across 315 extremely thin vertical screens (approx. 3cm x 300cm), spread over 7 stories.
Ward, Alistair   +2 more
core   +1 more source

Connecting connections

open access: yes, 2008
As true as it is that a bricklayer needs a plumb line and a T-square, so it is that a physicist using general relativity needs how to draw geodesics and use fields of congruent vector frames of reference. While the first part of the preceding statement depends on the Christoffel connection and related metric and curvature concepts, the second part ...
openaire   +2 more sources

Chaplain's flag from USS Columbus

open access: yes, 1945
This chaplain's pennant flag was flown from the USS Columbus, It is made of white canvas with a navy blue cross. On the side is rope and metal rings . The dimensions are 300 by 37cm. It was donated to the Ohio Historical Society, now the Ohio History

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