Results 111 to 120 of about 5,844,415 (324)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The Asymmetric Connection of SST in the Tasman Sea with Respect to the Opposite Phases of ENSO in Austral Summer [PDF]

, 2022
Xueqian Sun, Shuanglin Li, Stefan Liess
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Voltage abnormity prediction method of lithium-ion energy storage power station using informer based on Bayesian optimization

Scientific Reports
Accurately detecting voltage faults is essential for ensuring the safe and stable operation of energy storage power station systems. To swiftly identify operational faults in energy storage batteries, this study introduces a voltage anomaly prediction ...
Zhibo Rao, Jiahui Wu, Guodong Li, Haiyun Wang   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Barriers to finding and maintaining pet-inclusive affordable housing: Tenant experiences in Houston, Texas

Frontiers in Veterinary Science
The city of Houston, Texas has a growing deficit of available and affordable rental units for low-income residents. Due to pet policies, the shortage of affordable housing potentially puts renters who own pets at greater risk of housing insecurity.
Tess M. Mascitelli, Taryn M. Graham, Lauren Loney, Jennifer W. Applebaum, Christa M. Murray, Miranda Binns-Calvey, Sloane M. Hawes, Kevin Morris   +7 more
doaj   +1 more source

Connection between Celiac Disease and Systemic Lupus Erythematosus in Children—A Development Model of Autoimmune Diseases Starting from What We Inherit to What We Eat [PDF]

, 2023
Vasile Valeriu Lupu, Elena Jechel, Cristina Maria Mihai, Elena Cristina Mitrofan, Ancuța Lupu, Iuliana Magdalena Stârcea, Silvia Fotea, Adriana Mocanu, Dragos Catalin Ghica, Costică Mitrofan, Dragoş Munteanu, Delia Lidia Șalaru, Ionela Daniela Morariu, Ileana Ioniuc   +13 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Modeling and simulation analysis of multi-scenario air conditioning cluster response for intelligent load management in distribution networks

Scientific Reports
This paper proposes a dynamic multi-scenario modeling approach for air conditioning (AC) cluster loads, integrating occupant behavior, spatiotemporal activity distributions, and meteorological factors.
ZhiYong Zhang, HaiYun Wang
doaj   +1 more source