Results 31 to 40 of about 2,011,966 (289)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Sensitivity analysis of water consumption in an office building
E3S Web of Conferences, 2018 This article deals with sensitivity analysis of real water consumption in an office building. During a long-term real study, reducing of pressure in its water connection was simulated.
Suchacek Tomas +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Self-Organized Synchronization Phenomena in Spatiotemporal Coupled Oscillator Model for Emergent Systems [PDF]
Journal of Systemics, Cybernetics and Informatics, 2005 The author proposes a spatiotemporal coupled Lorenz model with an excitatory-excitatory connection or an excitatory-inhibitory connection, which consists of three temporal coupling coefficients c1,2,3 and three spatial coupling coefficients d1,2,3.
Tetsuji Emura
doaj
Investigations of friction-relevant parameters to ensure reliable bolted joints
MATEC Web of Conferences, 2017 During the process of torque-controlled tightening of bolted joints, the reliability of load transmission is limited by the achieved accurate preload. The preload is mainly influenced by head‐ and thread friction.
Klöcker Max, Westphal Sebastian
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Computing Connection Coefficients Of Compactly Supported Wavelets On Bounded Intervals [PDF]
, 1997 Daubechies wavelet basis functions have many properties that make them desirable as a basis for a Galerkin approach to solving PDEs: they are orthogonal, with compact support, and their connection coefficients can be computed.
Romine, C.H. +5 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CONNECTION BETWEEN PERFORMANCE TESTING METHODS IN HUNGARIAN PIG BREEDING BASED ON GENETIC CORRELATION COEFFICIENTS [PDF]
Poljoprivreda, 2000 Genetic analysis was conducted on Hungarian pig seed stocks. The breeds, which were used in the investigation, were Hungarian Large White, Hungarian Landrace, Duroc, and Pietrain respectively.
Istvan Nagy +3 more
doaj