Results 91 to 100 of about 292,639 (308)

Weyl-ambient geometries

open access: yesNuclear Physics B, 2023
Weyl geometry is a natural extension of conformal geometry with Weyl covariance mediated by a Weyl connection. We generalize the Fefferman-Graham (FG) ambient construction for conformal manifolds to a corresponding construction for Weyl manifolds.
Weizhen Jia   +2 more
doaj  

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

On connections on principal bundles [PDF]

open access: yesarXiv, 2016
A new construction of a universal connection was given in \cite{BHS}. The main aim here is to explain this construction. A theorem of Atiyah and Weil says that a holomorphic vector bundle $E$ over a compact Riemann surface admits a holomorphic connection if and only if the degree of every direct summand of $E$ is degree.
arxiv  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Mechanical behavior of 'Niagara Rosada' grape berry detachment Comportamento mecânico do destacamento de bagos de uva 'Niagara Rosada'

open access: yesEngenharia Agrícola, 2011
The 'Niagara Rosada' grape is the main Brazilian table grape belonging to the Labrusca family. It develops medium, cylindrical and compact bunches with berries presenting a pinkish skin and a foxy flavor that is valued in the Brazilian market.
Daniel Gomes, Antonio C. de O Ferraz
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Shape operator of an $ (n-1) $-dimensional distribution on an $ n $-dimensional manifold and their classification [PDF]

open access: yesریاضی و جامعه
This paper aims to study of shape operator of an $ (n-1) $-dimensional distribution on an $ n $-dimensional smooth manifold. In this study firstly we state formulae for the shape operator and its symmetric and anti-symmetric components and in ...
Mehran Aminian, Mehran Namjoo
doaj   +1 more source

Leafwise holonomy of connections over a bundle map [PDF]

open access: yesarXiv, 2002
In this paper we introduce a generalisation of the notion of holonomy for connections over a bundle map on a principal fibre bundle. We prove that, as in the standard theory on principal connections, the holonomy groups are Lie subgroups of the structure group of the principle fibre bundle and we also derive a straightforward generalisation of the ...
arxiv  

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